Molecular subtyping of breast cancer can better identify women at high risk of disease recurrence — ScienceDaily
source : http://www.sciencedaily.com/releases/2014/03/140306211042.htm
source : http://www.sciencedaily.com/releases/2014/03/140306211042.htm
source : http://www.sciencedaily.com/releases/2014/03/140304113534.htm
source : http://www.sciencedaily.com/releases/2014/01/140120085058.htm
Men who engage in higher levels of physical activity have been reported to have a lower risk of prostate cancer recurrence and mortality compared with men who participate in little or no physical activity. The biological mechanisms underlying this association are not known. "Prior research has shown that men with prostate tumors containing more regularly shaped blood vessels have a more favorable prognosis compared with men with prostate tumors containing mostly irregularly shaped blood vessels," said Erin Van Blarigan, Sc.D., assistant professor in the Department of Epidemiology and Biostatistics at the University of California, San Francisco. "In this study, we found that men who reported walking at a brisk pace had more regularly shaped blood vessels in their prostate tumors compared with men who reported walking at a less brisk pace…
The findings were presented October 28 at the 15th World Conference on Lung Cancer. Physicians look to lymph nodes to stage essentially all cancers, including mesothelioma. The presence or absence of metastatic cancer cells in lymph nodes affects prognosis and also typically dictates the optimal treatment strategy. But posterior intercostal lymph nodes, which are located between the ribs near the spine, have not been previously used to stage or guide treatment of malignant pleural mesothelioma or any other cancer. …
The findings, presented on Oct. 28, 2013, at the 12th annual International Conference on Frontiers in Cancer Prevention Research hosted by the American Association for Cancer Research, suggest that African-American women may be less likely to benefit from available HPV vaccines to prevent cervical cancer. HPV is a common sexually transmitted infection with more than 40 subtypes. The virus causes nearly all cases of cervical cancer, which begin as precancerous cervical abnormalities. …
The drug Zybrestat selectively targets and collapses tumor blood vessels, depriving the tumor of oxygen and making its cells die. In experiments involving a mouse model of pancreatic neuroendocrine tumors, Einstein scientists found that infusing mice with Zybrestat three times per week for four weeks resulted in significant antitumor activity compared with control mice given a placebo. The findings were presented in Boston at the American Association for Cancer Research-National Cancer Institute-European Organisation for Research and Treatment of Cancer International Conference on Molecular Targets and Cancer Therapeutics…
About 50 percent of melanomas, and less frequently other cancer types, harbor mutations in the BRAF oncogene. …
Antiangiogenic drugs are anticancer drugs designed to cut off the blood supply that brings tumors the nutrients they need to grow and survive, thereby starving and killing the tumor cells. …
Antibody-drug conjugates are a new type of targeted anticancer therapy, which use an antibody to deliver an attached drug directly to those cells that display the antibody’s target on their surfaces. This precision reduces the side effects of the attached drug compared with conventional systemic administration. Currently, there are two U.S…