Colon has safety mechanism that restricts tumor formation
The scientists have observed that the formation of an adenoma in the colon is accompanied by an increase in the production of a molecule called BMP (bone morphogenetic protein). …
Tag Archives: bmp
Bone growth factor may increase benign tumors but not malignant cancer
Other papers in the September Neurosurgery report on a stent-assisted approach for difficult-to-treat brain aneurysms and a new software program to help in identifying and protecting critical areas during brain tumor surgery. BMP Linked to Increased Risk of Benign Tumors Dr. Nandan Lad of Duke University Medical Center and colleagues analyzed the risk of cancers and benign tumors in nearly 4,700 patients receiving BMP as part of spinal fusion surgery. …
Research in fruit flies provides new insight into Barrett’s esophagus
A new study, published June 27, 2013 online in Cell Reports, suggests a different cause, namely a change in stem cell function, for this transformation. Researchers at the Buck Institute manipulated a signaling pathway (BMP-like Dpp) implicated in the development of Barrett’s esophagus. After manipulation, the adult stem cells that normally generate the lining of the esophagus of fruit flies morphed into the type of stem cells that generate stomach cells. "Up until this point, it’s not been clear what this signaling pathway does in stem cells of the gastrointestinal tract, or how it influences the regeneration of various types of epithelial cells in the gut of the fly," said Heinrich Jasper, PhD, a professor at the Buck Institute for Research on Aging and senior author of the study…