Tag Archives: based

New computer model may aid personalized cancer care

Reporting in the journal Cell Reports, researchers combined several types of data from pre- and post-treatment biopsies of breast tumors to obtain a molecular picture of how the cancer evolved as a result of chemotherapy. “Better understanding of tumor evolution is key to improving the design of cancer therapies and for truly individualized cancer treatment,” said Kornelia Polyak, MD, PhD, a breast cancer researcher. The model was developed by Polyak and Franziska Michor, PhD, a computational biologist at Dana-Farber. …

Research proposes alternative therapy against lung cancer

"It has been considered that the upturn in cases of lung cancer is possibly related to this particles," explains Patricia Gorocica from the INER, who, alongside her research team, has been working in an alternative therapy to boost the immune system of patients with this disease. The specialist adds that since several years ago is known that the immune system has all the mechanism to watch and destroy tumor cells as they develop, but sometimes this mechanisms are not effective for reasons associated to the tumor or alterations of the patients organism. Based in this principle, research at INER is directed to regulate the immune system against tumors. …

Surviving survival

In the largest study of its kind, researchers led by the University of Pennsylvania School of Nursing have investigated the caregivers of 186 mothers to childhood brain tumor survivors aged 14-40 whose care needs last long into adulthood. They based their research on a model containing factors central to nursing practice, namely the caregiver, the survivor, and the family. They discovered that a complex interaction among components of the model, the health of the caregivers, the demands experienced by the caregiver, the caregiver’s perceptions about the health of the survivor, and the family’s support interact to explain how the caregiver assesses herself in her role. …

Higher than normal levels of Vitamin B12 may indicate cancer risk

To assess the association between high Cbl levels and risk of cancer of any type, Johan Arendt, BSc, of the Department of Clinical Epidemiology and the Department of Clinical Biochemistry of Aarhus University Hospital in Denmark, and colleagues used Danish Medical registries to review the records of 333,667 patients without cancer who had been referred for Cbl testing and to estimate the incidence of cancer in this population from 1998 to 2010. The researchers excluded patients who had a cancer diagnosis before the date of plasma measurement and those who were receiving Cbl therapy. They found that the risk of cancer overall increased with higher Cbl levels, especially during the first year after measurement and for those with levels > 800pmol/L. …