More than 70 per cent of women who have had breast cancer experience menopausal problems, and hot flashes in particular, which are among the most prevalent and potentially distressing problems following breast cancer treatment. These can also be long lasting, persisting for more than five years once cancer treatment has ended and affecting all aspects of life, including sleep, social situations, intimate relationships and ability to work…
“Genetic alterations in cancer in humans may involve gene inactivation, amplification or inactivation,” said List.These changes are not present in nonmalignant cells. Common chemotherapeutic agents aggressively kill tumor cells irrespective of genetic alterations.They also have a negative impact on normal cells and can cause significant side effects. …
Their investigation began with only a tiny blood platelet, but quickly they discovered opportunities for growth and expanding the breadth of the research. “We have a lot to gain by looking at platelets and how they influence cancer and healing,” said Dr. Camillo Bulla. …
The researchers identified a protein known as CD47 as a molecular imaging target to distinguish bladder cancer from benign tissues. In the future, this technique could improve bladder cancer detection, guide more precise cancer surgery and reduce unnecessary biopsies, therefore increasing cancer patients’ quality of life. The work is described in a paper that will be published Oct. 29 in Science Translational Medicine…
Renata Jaskula-Sztul, Ph.D., University of Wisconsin Medical School (Madison), and colleagues will deliver an oral presentation entitled “Targeted Delivery of a Novel Histone Deacetylase Inhibitor, AB3, Using Unimolecular Micelles to Improve Antitumor Effect in Medullary Thyroid Cancer.” MTC is a neuroendocrine tumor that accounts for 3-5% of thyroid cancers. …
A team of biomedical engineers at Vanderbilt University headed by Assistant Professor Melissa Skala has developed the technique, which uses fluorescence imaging to monitor the response of three-dimensional chunks of tumors removed from patients and exposed to different anti-cancer drugs. In an article published last month by the journal Cancer Research the engineers describe applying the technique to the three major forms of breast cancer. They report that the test can detect significant drops in the metabolic activity levels of all three types of tumors within 72 hours when exposed to an effective drug whereas tumors that were resistant to a drug show no change…
Researchers examined thyroid cancers diagnosed up to two decades after the Chernobyl accident and found that higher thyroid radiation doses estimated from measurements taken shortly after the accident were associated with more aggressive tumor features. “Our group has previously shown that exposures to radioactive iodine significantly increase the risk of thyroid cancer in a dose-dependent manner. The new study shows that radiation exposures are also associated with distinct clinical features that are more aggressive,” said the paper’s first author, Lydia Zablotska, MD, PhD, associate professor in the Department of Epidemiology and Biostatistics at UC San Francisco (UCSF). The paper will be published online in the journal Cancer…
Dr. …
A team of biomedical engineers at Vanderbilt University headed by Assistant Professor Melissa Skala has developed the technique, which uses fluorescence imaging to monitor the response of three-dimensional chunks of tumors removed from patients and exposed to different anti-cancer drugs. In an article published last month by the journal Cancer Research the engineers describe applying the technique to the three major forms of breast cancer. …
Researchers at M.D. …