The use of esophageal cancer drugs fluorouracil

By | March 20, 2012

The use of fluorouracil, fluorouracil do arteries, veins, intratumoral injection can also be oral, dose types of disease-specific illness. 1 time per week generally, each 750mg; or 2 times a week, each 500mg intravenous injection or intravenous drip.
The use of fluorouracil (1) intravenous infusion. 15mg/kg dissolved in 5% glucose injection or saline infusion 2_3h, 1 time per day for 5 days, after halving the dose every other day for a time, until the emergence of toxicity; or per 10-20mg / Zhi general to 500mg/ml, dissolved in 5% glucose injection 500_1000ml, the infusion of 6 – 8h, every 10 days for a course of treatment. IV: 500_750mg / times, 1 time per day for 5 days, after halving the dose every other day for a time, until the emergence of toxicity; or per 10-20mg / Zhi, a course of total 5_7.5g. Combination: each 300_500mg/ml, intravenous infusion, 2 times per week, or 24h continuous intravenous infusion, once every 5, 3 weeks.
Fluorouracil usage (2) orally. Single drug, each 50_100mg, day 3 – 4 times, the total 10_15g.
(3) arterial perfusion. Such as the liver with hepatic artery infusion (pump or retained catheter set), each 500_600mg/ml, plus 5% glucose solution 1000ml, or continuous infusion 6_8h 24h, 3 times a week for 4 weeks as a course of treatment. Intervention, each 1000_1250mg, 4 weeks 1 times.
The use of fluorouracil (4) treated with local administration. For skin cancer or cancerous ulcer, 5% _10% of the fine ointment or cream applied to lesions, 1_2 times a day, medication required before debridement.
The use of fluorouracil (5) pediatric use. IV, 5_15mg/kg, used in conjunction 3-6 days instead of every 7.5mg / candle, every other day 1, the total 90_100mg/kg to a course of treatment, repeated every 1_2 months after the first 2 courses.

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