Chemotherapy treatment due to gastrointestinal reactions

By | December 9, 2011

Chemotherapeutic drug-induced gastrointestinal reactions such as nausea and vomiting in patients with symptoms of one of the most fear of side effects of chemotherapy, can seriously affect the quality of life of patients, and even the patient refused chemotherapy. The incidence of symptoms and severity with chemotherapy drugs, dosage and patient to my question. 70% ~ 80% of the patients receiving chemotherapy experienced nausea and vomiting, 10% to 44% of patients receiving chemotherapy experienced nausea and vomiting expectations. Here is the gastrointestinal tract caused by chemotherapy drugs feel the symptoms of several responses:
Chemotherapeutic drug-induced gastrointestinal reactions (1) nausea and vomiting, is the most common chemotherapy side effects, especially DDP ,5-FU and other adverse reactions, some patients respond so serious that chemotherapy difficult, also reduced the patient quality of life. Before treatment should be well explained to patients and their families work, tell the patient nausea and vomiting is a temporary, or do not directly tell patients. Easy to cause gastrointestinal side effects of chemotherapy, or some patients have mental effects, only good food for their guidance. Get up early the day before chemotherapy, activities backward nutritious breakfast, eating time normally scheduled for 6:00 or so, eating species for small rice, boiled eggs, pickle slices, a small amount of pasta, not into sweets, reduce the food easily cause flatulence such as milk, soy milk and so on. Later to eat lunch, eat light digestible diet, do not eat 1 hour before chemotherapy or less to eat, it is best to chemotherapy drugs after a meal 2-4 hours later to eat dinner, so not only ensure the nutrition and reduced gastric gut reaction. Antiemetic drugs, the clinical application of more is Oubei, in the course of intravenous chemotherapy, usually give the first liver antiemetic drugs, infusion flow is indeed confirmed in the blood vessels within the needle before injection antiemetic agents and enhance the detoxification of drugs and drug sensitivity to chemotherapeutic drugs, and then infusion of chemotherapy drugs, which can reduce phlebitis and gastrointestinal reactions.
Chemotherapeutic drug-induced gastrointestinal reaction (2) loss of appetite, most patients have loss of appetite during chemotherapy situation, and even some patients can not eat, increase the patient's pain, affect the treatment.
Treatment: give antiemetic drugs, nausea and vomiting to reduced to a minimum. Eat small meals often, the patient may enter the food like, non-greasy food. given high-protein, high in vitamins and fresh vegetables, fruits, such as cucumber, a small amount of water Luoka other food should be concise, more flavor transformation to improve the appetite, if necessary, give intravenous nutritional support.
(3) constipation, neurotoxicity induced by chemotherapeutic agents and antiemetic drugs, acting on the gastrointestinal smooth muscle, the motility decreased, causing constipation.
Treatment: the patient into the high-fiber diet (celery, spinach, leeks, etc.) and purge food (cooked sweet potatoes, bananas, honey, etc.) and more water. encourage appropriate activities. give enema to soften stools. diarrhea, diarrhea medicine may be given, if necessary, intravenous hydration and nutrition.

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