Method of interventional therapy

By | November 15, 2011

Embolization are the following methods:
Interventional Therapy (1) chemotherapy
Chemotherapy is a concentration of forces attack the tumor treatment, ie, after the arterial catheter, the drug injected directly into the liver locally. It is the peripheral arterial catheter delivered through the hepatic artery after drug injection through the catheter directly to the lesions on the liver. With traditional intravenous administration (infusion) compared to its lower systemic toxicity; the same time, the use of selective arterial infusion, the drug can increase the local concentration of liver cancer. Dosage does not increase in the case of drug concentrations within the tumor tissue than normal tissue drug concentrations 5-20 times higher, thus effectively improving the therapeutic effect.
Liver cancer intervention (2) Transcatheter embolization
In our battle with cancer, in addition to concentrating a superior force attack, there is another strategy, that is, cut off the enemy's food channel, so that the loss of the enemy combat capability. Transcatheter embolization is the treatment strategy used, it is a catheter into the hepatic artery, by contrast find the nutrient vessels of the tumor, transcatheter infusion embolization agent, blocking the tumor blood vessels, to block the tumor blood supply and nutrition purposes . Its principle is this: the normal tissues and organs to only feeding arteries and draining veins, the blood from the artery into the tissue, tissue from the venous outflow. Different with the general organization of the liver, it is not only like other organizations, have their own feeding arteries and draining veins (ie, hepatic artery and hepatic veins), it also has a portal supply of nutrition. That is, accept the hepatic artery and hepatic portal vein blood supply; which accounted for 25% of the hepatic artery, portal vein blood 75%; liver cancer is different, it's blood supply 95% -100% from the hepatic artery. After hepatic artery embolization, liver blood supply more than 90% reduction, while the normal liver tissue blood flow decreased by only 30% – 40%. Therefore, if only the arterial blood supply to the tumor injection of embolic agents, can cause cancer tissue necrosis, but little effect on normal liver tissue. Currently, for unresectable hepatocellular carcinoma, transcatheter arterial chemoembolization (TACE) has become the preferred non-surgical therapy.
Interventional Therapy (3) intervention by the portal vein
We have just mentioned, the liver has a dual blood supply. In some patients, the tumor blood supply in addition to be, but there is a branch of the portal vein as it provides nutrition, in such circumstances, in order to achieve better therapeutic effect, addition to the above description of the hepatic arterial chemoembolization, can also by percutaneous, catheter infusion into the portal vein chemotherapy and embolic agents. Chemotherapy drugs in low voltage, low portal vein flow velocity, continuously, more sustained exposure of tumor cells play a role in cancer. This approach especially from other parts of the tumor metastasized to the liver is better.

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