Esophageal cancer treatment

By | May 6, 2012

Esophageal cancer treatment (a) general treatment
1 To encourage patients to maintain a good mood thinking in order to avoid emotional instability and worse. If the patient cough. Timely and appropriate to give pain medications, such as cough agents, analgesic agents, and other appropriate measures to reduce the treatment of patients with pain.
2. To find ways to allow patients to eat, especially for patients for some semi-liquid, fluid juice rich in vitamins, protein, trace elements in food. Guarantee the supply of calories and nutrients.
3. To prepare a cold temperature were suitable, comfortable and quiet environment, and prevent environmental factors for patients to bring psychological and physical discomfort worse.
Esophageal cancer treatment (b) western medicine
1. Surgical treatment
At present, a surgical treatment of esophageal cancer 5-year survival rate was 90%. In recent years, the consistent improvements in technology, the extensive application of stapler, anastomotic leakage Pat down to about 3%. Most scholars believe that: the earlier patients, surgery can achieve more satisfactory results, for most patients, palliative surgery had a positive therapeutic effect.
Basic operation plan are: through left esophageal resection and intrathoracic esophagogastric anastomosis; through left cervical esophageal resection and anastomosis of esophagus and stomach; by right thoracic esophagectomy and intrathoracic esophagogastric anastomosis; esophageal Results stomach cancer and esophageal resection anastomosis; reversed gastric tube reconstruction in esophageal surgery. With esophageal cancer and surgical procedures based on further study, indicates that comprehensive treatment based on surgical treatment of esophageal cancer will be further improved.
2. Radiation Therapy
Radiation therapy with less damage to adapt to wide range of surgery. Radiation treatment of esophageal cancer on the medium sensitivity. Esophageal cancer is generally high compared with the lower middle is more suitable for radiation therapy of esophageal cancer. There are three commonly used in radiation therapy: intracavitary irradiation, irradiation and in vitro exposure within the organization. Intracavitary irradiation to use more effective drilling length 5-7cm linear sources, external irradiation to 60 cobalt sources often, the use of three-field irradiation (ie, the vertical field chest, back, oblique two-field).
(1) radical radiotherapy: Indications generally moderate, no supraclavicular lymph node metastasis, silent with paralysis, without distant metastasis, tumor short 7cm, narrow and not significant, no significant thoracodorsal pain, no perforation of X-ray findings.
(2) palliative radiotherapy: patients to alleviate pain and prolong life. The effect of radiotherapy patients, it is timely to radical radiotherapy.
3. Endoscopic microwave, laser, intubation
In the endoscope, the coaxial needle into the lesion in, select the appropriate power for microwave coagulation treatment of 2 4 times to receive some palliative effect. Microwave treatment within the required equipment for the Olympus IF-QI0 (MB-3W) treatment endoscopy, WN-I-type microwave cavity treatment device (frequency of 2450MHz, wavelength of 12cm, the microwave power (0 70W), coaxial cable and so on.
4. Intracavitary hyperthermia
Hyperthermia combined with radiotherapy of esophageal cancer, combined hyperthermia and chemotherapy or radiotherapy can get good results. Hyperthermia, the first X-ray positioning, to determine the depth of insertion of radiation,) treatment, according to the patient's condition, from the oral or nasal cavity insert, generally do not have the surface of paralysis. Heating time is 45-60 minutes, so that esophageal cancer to 47-50 C degrees. 1-2 times a week, a total of 5-6 times.
5. Chemical drug therapy
Standard chemotherapy of esophageal cancer are the following
(1) CVB programs
Cis chloramine platinum: 3mg/kg or 120mg/m2. D (high dose used with caution), IV, the first day
Changchun amide: 3 mg / m 2. D, IV, 1, 8, 15 and 22 days
BLM: 10mg/m2. D, IV (loading dose), continuous intravenous infusion, the first 3 6 days. Repeat 1 time in 4 weeks and then stop bleomycin. Cis platinum chloramine 1 every 6 weeks, Changchun amide 1 every 2 weeks.
(2) FAP program
5 fluoro-ethyl FU: 600mg/m2. D, IV, 1, 8 days
DOX: 30mg/m2. D, IV, day 1
Cis chloramine platinum: 75 mg/m2. D, IV, day 1 while providing: "hydration" and mannitol diuresis. If tolerated, repeated every 4 weeks 1.
(3) MBC program
A chlorine neopterin: 40mg/m2. D, IV, No. 1, 14 days
BLM: 10mg/m2. D, IV, 1, 8, 15 days
Cis chloramine platinum: 50mg/m2. D, IV, 4 days, the first 21 days 1.
(4) MF program
MMC: 10mg/m2. D, IV, day 1
5 – fluorouracil: 1000mg/m2. D, continuous static Li River, the first 1-4 days and 29-32 days, the program used for surgery and radiotherapy.
(5) DF program
Cis chloramine platinum: 100mg/m2. D, IV, day 1
Treatment of esophageal cancer 5 – fluorouracil: 1000mg/m2. D, IV, 1, 8 days, repeated every 21 days one time, sharing 3 cycles, then surgery or radiotherapy.
In addition to the above options, domestic scholars with a single carboplatin treatment of the disease. Carboplatin is a second generation of metal platinum anticancer drugs. Cisplatin is considered a better alternative to drugs for the treatment of advanced esophageal cancer with low toxicity and better efficacy, chemotherapy index is high.
Usage: carboplatin 350 – 400mg/m2, diluted in 500ml of 5% glucose intravenous drip. 1 every 4 weeks.

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