Chemotherapy of pancreatic cancer

By | May 5, 2012

Pancreatic cancer chemotherapy, due to pancreatic cancer insidious onset, atypical symptoms, mostly in the late discovery violations and the surrounding organs or large blood vessels have distant metastasis, and thus less able to surgical resection. Therefore, other treatment is widely used, the most commonly used chemotherapy and radiation therapy. Chemotherapy for a long time, during the treatment of pancreatic cancer through clinical testing of chemical drugs 5 fluorouracil slightly a hospital, mitomycin, chain gills adriamycin, cyclophosphamide different route glue, BCNU, doxorubicin, Epirubicin, a cyclohexyl nitrite gills, Changchun gaze intently rubber, ammonia, a butterfly Ridge, actinomycin and so on. In fact, almost all chemotherapy drugs may be effective in the treatment of pancreatic cancer application before. It is hoped that effective in other cancer therapy as effective as drugs for pancreatic cancer.
It is worth mentioning that Gemzar, gemcitabine is the recent emergence of pancreatic cancer treatment is a major progress in the introduction was hailed as the beginning of hope for patients with pancreatic cancer. Gemcitabine is the body through the intervention of genetic material DNA that is important to the synthesis of DNA, to inhibit tumor growth purposes. It is similar in structure and metabolism slightly eyelashes oxygen cell as a prodrug, can be phosphorylated to become active metabolites which play a role. More special because of its mechanism of action of gemcitabine in the treatment of pancreatic cancer a significant effect, the current research is under way. We also observed in clinical work progress of the disease to this drug in control and improve the symptoms certainly has some effect.
Chemotherapy of pancreatic cancer, pancreatic cancer chemotherapy can be divided into two kinds of single agent and combination therapy. More common for a single drug programs, including 5 fluorouracil slightly Anhui, mitomycin, chain gills adriamycin, cyclophosphamide gaze intently different plastic, gemcitabine and so on. Commonly used chemotherapy regimens, including SMF (ADM chain gills for a ten 5 fluorouracil mitomycin little ten homes), FAM (5 A little hospital ten fluorouracil Adriamycin + mitomycin), etc., than the single drug improve the efficacy of the program there. In recent years, based on the combined use of gemcitabine and other chemotherapy drugs such as Eloxatin, a series of paclitaxel and other ongoing clinical trials, its efficacy will soon be reported.

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