Squamous cell carcinoma of the lung peripheral

By | March 30, 2012

Peripheral pulmonary squamous cell carcinoma in peripheral lung squamous cell carcinoma, squamous cell carcinoma as target type (peripheral squamous cellcarcinoma), referred to as peripheral squamous cell carcinoma. Peripheral squamous cell lung cancer accounts for 7% of the total number of 14%.
(1) histological features and clinical: peripheral pulmonary squamous cell carcinoma of the age, sex, location, tumor size and organizational structure, and the central roughly the same. Size is generally small, but often accompanied by cavitation. Lung cancer with cavity formation, most of the histological type is squamous cell carcinoma. Characteristics of peripheral pulmonary squamous cell carcinoma as follows: fewer symptoms; well differentiated cancer cells, the majority belong to the differentiation of squamous cell carcinoma (SCC most central of squamous cell carcinoma is a low juice); invasion of lymphatic weak; hilar lymph node metastasis was low; at 5-year survival rate is higher.
(2) differential diagnosis:
squamous cell carcinoma of the lung peripheral adenocarcinoma of the identification and implementation of key points: a. whether the hierarchical structure: state of implementation of gonads showed no hierarchical structure; peripheral squamous cell carcinoma showed a hierarchical structure; b. the number of mucus: Real gonadal cancer, cancer cells secrete fluid is easy to see taught, and the secretion of peripheral squamous cell carcinoma but not new or occasional liquid; c. is easy to form a cavity: surgical resection specimens, voids form around the more common type of squamous cell carcinoma, and solid adenocarcinoma necrosis, but less than the formation of voids.
peripheral pulmonary squamous cell carcinoma and large cell carcinoma, identification of key points: a. basal cell-like large cell carcinoma, although the nest week also showed a palisade cells, but the hierarchy is not obvious, and the peripheral squamous cell carcinoma of the sub-nest layer structure significantly; b. peripheral squamous cell nests can always find the central keratinization, and even the formation of a large number of keratosis, and basal cell-like large cell carcinoma cells is not display the morphological characteristics; c. large cell carcinoma, basal cell-like mitotic index is high, the average 70/10HPF, the mitotic index was lower in peripheral squamous cell carcinoma, the average 24/10HPF; d. basal cell-like large cell carcinoma, mostly large necrosis, and peripheral squamous cell carcinoma often has small focal necrosis; e. like large cell carcinoma, basal cell necrosis section bleeding obvious, and common cavity formation of peripheral squamous cell carcinoma.

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