Lung squamous cell carcinoma Introduction

By | March 30, 2012

Introduction of lung squamous cell carcinoma, lung squamous cell carcinoma (spuamous cell carcinoma) is a lung IMl, supporting common histological type, occurs in the lungs (bronchi) in epithelial tumors, highly malignant cells more common angle microscope oriented and (or) cell bridge.
Multiple origins in the lobar bronchus, segmental bronchi and subsegmental bronchi, so the central squamous cell carcinoma of the lung, but also a small number of squamous cell carcinoma of the lung is a peripheral. Squamous cell carcinoma mostly horizontal bar; have multiple. Faster than the growth of lung squamous cell carcinoma, but transferred later than adenocarcinoma, squamous cell carcinoma deduction occurs late hilar and mediastinal lymph node metastasis lymph nodes and distant metastasis rare. Middle-aged men who smoke as high-risk groups, the incidence of smoking and daily cigarette consumption is proportional to age.
Introduction of lung squamous cell carcinoma, squamous cell carcinoma after 5-year survival rate was 20% -25% on average, better prognosis than adenocarcinoma. Actress factors, mainly for clinical stage and tumor volume. Generally believed that tumor cell differentiation, tumor necrosis, lymphatic invasion and blood channel was no significant correlation with the prognosis.
The naked eye, the tumor was gray, such as necrosis of the pale yellow color; tumor and surrounding lung group less! Boundaries unclear, larger tumors, cancer often necrosis, the formation of cancerous empty. Destruction of tumor bronchial wall, infiltrating the surrounding lung parenchyma, or to the cavity and protruding air significantly narrowed bronchial involvement. Histological features of squamous cell carcinoma and other parts of the same. The basic structural features are: cancer nest with a hierarchical structure, ie, noncancerous cells were basaloid arrangement, but the nest more mature central cell differentiation, abundant eosinophilic cytoplasm similar spike cells. Cancer cells have different levels of nest cell keratinization, keratin pearls or accompanied by the formation of intercellular bridges.
Lung squamous cell carcinoma of the introduction, according to different levels of cell keratosis, squamous cell carcinoma is divided into the classic well-differentiated lung squamous cell carcinoma, squamous cell carcinoma and poorly differentiated squamous cell carcinoma. More common in poorly differentiated squamous cell carcinoma, well differentiated squamous cell carcinoma rare, moderately differentiated squamous cell carcinoma in between. Differentiated squamous cell carcinoma and poorly differentiated carcinoma, squamous cell carcinoma accounts for about 90%.

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