What are the risk factors of nasopharyngeal carcinoma

By | December 5, 2011

NPC 's exact cause has not yet understood, but genetic factors, viral infections, living environment, oncogenes, etc. can find some clues.
Nasopharyngeal carcinoma treatment factors 1. EB virus is a herpes virus which is pathogenic factors lead to one of nasopharyngeal carcinoma, nasopharyngeal carcinoma patients and more can be found in the EB virus. The relationship between EB virus and nasopharyngeal carcinoma have been used for clinical diagnosis and prognosis. EB virus infected cells can produce a variety of EB virus-specific antigens, including early antigen (EA), capsid antigen (VCA) and so on. EB virus infection in humans can produce a corresponding variety of antibodies. EB virus in patients with nasopharyngeal carcinoma EA-IgA and VCA-IgA-positive rate of technology were 95% and 81. 5% 0 EA-IgA and VCA-IgA immune system through the identification and nasopharyngeal precancerous lesions and early cancer clonal growth the virus replication, thus reflecting the biological characteristics of nasopharyngeal carcinoma. High sensitivity of VCA-IgA, EA-IgA with high specificity, if the VCA-IgA and EA-IgA antibodies were positive, then the risk of nasopharyngeal cancer is very high.
2 factors of nasopharyngeal carcinoma treatment. Environmental another nasopharyngeal cancer risk factors, dietary nitrite rubber, chemical carcinogens in the environment, they may be completed in two complementary ways, either through direct gene action, or by activating the role of EB virus.
3 factors of nasopharyngeal carcinoma treatment. Genetic factors were mainly seen in yellow NPC, particularly the Pearl River Delta in Guangdong Province in China speak Cantonese dialect along the Xijiang River were the highest incidence of local residents even moved to other provinces, even long-term residence in foreign countries, but also still have a higher incidence of living in Greenland Eskimos, the probability of suffering from nasopharyngeal carcinoma 30 times higher than the local whites. This indicates that genetic factors and the nasopharyngeal carcinoma occurrence and development. Human histocompatibility antigen (HLA) locus mutation. And is closely related to nasopharyngeal carcinoma. And the incidence of risk factors associated with H2 antigen, BW46 antigens, B17 antigen, is another research hotspot.
4 factors of nasopharyngeal carcinoma treatment. Oncogene research has shown that NPC cells the expression of ras oncogene and tumor suppressor gene loss.

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