Gastritis, gastric ulcer, whether gastric cancer and the like? Which many people are concerned about. Some diseases, leading to cancer of the stomach diseases such as chronic atrophic gastritis, chronic gastric ulcer, gastric polyps, gastric remnant, etc., due to the internal environment and external environment changes, you can further develop a cancerous condition called pre-cancerous disease.
Lead to stomach cancer disease 1. Atrophic gastritis
Prolonged low acid and emptying of the role of increased carcinogen. 80% -90% cancer patients with atrophic gastritis, atrophic gastritis were followed up for 10-20 years, the incidence of gastric cancer is about 5% -10%. Gastritis, gastric cancer, the process of evolution of the basic follow this pattern: superficial gastritis, atrophic gastritis, a one intestinal metaplasia and dysplasia of a gastric cancer. Simple atrophic gastritis, especially in mild to moderate atrophic gastritis, cancer rates of small, moderate and severe atrophic gastritis with moderate or severe intestinal metaplasia and severe dysplasia, are considered pre-cancerous lesions.
(1), gastric epithelial dysplasia and intestinal metaplasia
Gastric epithelial dysplasia and intestinal metaplasia are precancerous lesions of gastric cancer, is the pathological changes of gastric mucosa, which teaches film than the normal gastric mucosa cancer-prone, that is, all the gastric cancer, gastric histological changes, must pass the stage. Gastric dysplasia, especially severe adenomatous hyperplasia, the cancer rate is highest.
Gastric dysplasia refers to the growth of gastric mucosa morphological deviation from the normal tissue structure and cell differentiation, is the main precancerous lesions. Gastric epithelial dysplasia are generally divided into mild, moderate, and severe levels. More than mild dysplasia that no important clinical significance, may be followed up or were followed up for longer intervals, moderate and severe dysplasia should be followed up, and some severe dysplasia and gastric cancer not easy to distinguish and feasible surgical treatment.
Intestinal metaplasia is the intestinal metaplasia of gastric mucosa, it is normal to be intestinal type gastric epithelial epithelial teach replaced. See the light in only a small number of intestinal epithelial cells, re-formation of intestinal villi are visible. Intestinal metaplasia of the gastric mucosa with a normal gastric mucosa does not have the absorptive capacity, can absorb some of the fat-soluble carcinogens. However, this metaplasia is hypoplastic intestinal epithelial cells, although the lack of transport function can absorb it, so they remain absorbed carcinogens easily understood in the mucosa lead to gastric carcinogenesis. IM is divided into the small intestine and large intestine-type metaplasia type metaplasia. The latter is closely related with gastric cancer, is the precancerous lesions.
It is worth noting: both gastric precancerous disease or precancerous lesions of gastric cancer does not necessarily occur, but most patients will be cured and can be reversed, stop or disappear naturally, only a small part of the cancer. Therefore, please do not misunderstand that would make the sufferers of stress.
(2) ways to prevent atrophic gastritis
Regular endoscopic follow-up is very important, especially associated with polyps, dysplasia or a focal depression or uplift of the importance to strengthen the follow-up should be based on clinical symptoms, endoscopy 3-6 months to do a biopsy. Reduce the spicy food, eat more dairy products and fresh vegetables with a lot of vitamins. Non-paid liquor and binge eating, eating smoked food armpit. Chinese medicine is effective and the treatment of this disease, intestinal metaplasia and atrophic lesions may be reversed.
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- can metaplasia lead to dysplasia
- gastro disease that can lead to cancer