Anorexia and cachexia relationship

By | March 26, 2012

Relationship between anorexia and cachexia: When anorexia is a complex disorder, cachexia is caused by air of the main factors in patients with appetite loss are common symptoms of cancer, but also often accompanied by his hatred, the vision changes, nausea, vomiting and other symptoms. Anorexia for many reasons, or because the material expansion of the side effects of chemotherapy, because the liver damage, or because of prolonged fever, or because of pain, so that cattle eat the brain dysfunction caused by regulation center.
Under normal circumstances, consumption depends on the hypothalamic feeding center and the balance between central satiation. Animal experiments showed that the tumor growth process, the central and peripheral factors involved in the occurrence of anorexia. Blood glucose and blood fatty acid levels, outside temperature, osmotic concentration, the concentration of plasma amino acid changes that affect the eating behavior are the peripheral factors, including plasma amino acid concentration on the impact of diet is particularly noticed by the people.
Relationship between anorexia and cachexia: Currently there are two categories that neurotransmitter systems, namely tryptophan catechu gum and hope the system plays an important role in the food, especially the latter animal experiments show that the brain concentration of women with anorexia on colored plastic. When the brain tryptophan is the amount of plasma free tryptophan and neutral amino acids and ammonia free color to adjust the ratio, because of free tryptophan and neutral amino-as in the brain through a common carrier transport, and therefore plasma free tryptophan levels or the plasma concentration of tryptophan, brain tryptophan concentration in the hypothalamus can lead to 5 – color gel synthesis, and improvement in gum concentration in the brain was associated with anorexia.
Relationship between anorexia and cachexia: the local effects of the tumor itself is another factor that led to reduced consumption, especially gastrointestinal cancer, such as the mouth, pharynx, esophagus cancer patients, due to swallowing difficulties, reduced intake of food made obstacle. Stomach cancer caused by obstruction, abdominal distention, nausea, vomiting, resulting in eating less, loss of appetite. Patients with liver metastases often accompanied by liver failure, liver can not remove the tumor produced by anaerobic metabolism of glucose, lactic acid, resulting in anorexia and nausea. In addition, psychological factors, depression, anxiety, also can affect appetite.
Numerous studies show that the relationship between anorexia and cachexia, cancer patients with anorexia led to reduced food intake, due to cachexia, anorexia and simple cachexia caused by the protein, fat and carbohydrate metabolism have not unusual to ask.

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