Liver toxicity of chemotherapy, 1. Part of the chemotherapy drug into the stomach, duodenum, gall bladder, can cause mild gastrointestinal reactions, manifested as anorexia, nausea and vomiting. Should be given to symptomatic treatment, such as preoperative 5-HT3 receptor in the blocker, metoclopramide (metoclopramide) and so on.
2. High-dose chemotherapy drugs can cause abnormal vascular structure damage, mainly for the hepatic artery and its branches narrow, irregular as well as total occlusion or aneurysm formation. Slow delivery, combined with anticoagulant drugs can reduce its incidence.
3. A small number of bone marrow suppression may occur in patients with acetabular cells decreased significantly, should be closely observed, if necessary, be given Whale blood (non-cell Division kiosks) and other drug treatment rose white blood cells.
4. Hair loss in varying degrees, but little effect on the efficacy after stopping more recoverable.
Liver toxicity of chemotherapy drugs, 5. Heart, liver, kidney toxicity ADM and its derivatives, can lead to cardiac toxicity, dosage should be strictly controlled, especially the elderly or those with potential heart disease, and to vitamin E, coenzyme QIO other treatment. Most chemotherapy drugs can cause liver damage, cirrhosis of the liver increased the process, therefore, should also use liver protection drugs, such as Glucurolactone (Portugal cavity enzymes), and other powerful Ning. DDP nephrotoxicity significantly, especially in large doses (usually more than 80mg), it must be hydration treatment.