Cancer drug – blood circulation drugs

By | April 25, 2012

Cancer drug – blood circulation drugs, traditional Chinese medicine turmeric curcumin is the main active ingredient. Studies have looked at the impact of curcumin on angiogenesis, using electron microscopy and flow cytometry curcumin induced tumor apoptosis in SMMC-7721 cells. The results showed that curcumin inhibits tumor angiogenesis mechanism are: the cell cycle and induction of apoptosis, direct inhibition of tumor vascular endothelial cells; reduction of tumor vascular endothelial growth factor (VEGF) gene expression, decreased cell VEGF level; inhibition of matrix metalloproteinase activity.
Norcantharidin hormone (NCTD). NCTD is separated from the extraction of traditional Chinese medicine cantharidin its active ingredients, NCTD can inhibit the growth of tumor cells in vitro. Researchers are testing NCTD on human umbilical vein endothelial cells (HUVEC) cytotoxicity, the results showed that NCTD on growth of HUVEC significantly inhibited. NCTD caused by the inhibition of HUVEC growth, apoptosis is only one part of the reason is not dominant, and is the root cause necrosis; NCTD can increase the nuclear transcription factor NF-B in the expression of inhibitory molecules IBa, suggesting that the tumor disease process, such as around the tumor can be inhibited NCTD-induced proliferation of endothelial cells, can control the further development of tumor tissue.
Cancer drug – blood circulation drugs, CAE-BCAE-B is the active ingredient in hematoxylin. HE has blood circulation, the role of swelling and pain. The last century, Japanese scholars have found in vitro hematoxylin water extract inhibited tumor cells, but also found that water extract hematoxylin Ehrlich ascites carcinoma in mice was inhibited. Tumor specific growth factor (TSGF) capillaries surrounding the tumor cells and the material basis for a large number of amplification in tumor formation in the early release into the blood, promote blood vessel growth. The anti-cancer active ingredients hematoxylin CAE-B significantly decreased the serum of tumor-bearing mice TSGF value, indicating that CAE-B can lead to obstruction around the tumor angiogenesis, inhibit tumor growth and development.

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