3-D culture system for pancreatic cancer has potential to change therapeutic approaches
In work published in Cell, the research team describes a three-dimensional “organoid” culture system for pancreatic cancer. …
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Researchers map paths to cancer drug resistance — ScienceDaily
By mapping the specific steps that cells of melanoma, breast cancer and a blood cancer called myelofibrosis use to become resistant to drugs, the researchers now have much better targets for blocking those pathways and keeping current therapies effective. The findings are published in two papers Dec…
Whole-genome sequencing can successfully identify cancer-related mutations
This is the first study that has used whole-genome sequencing to evaluate a series of 258 cancer patients’ genomes to improve the ability to diagnose cancer-predisposing mutations. The study is published online in the journal EBioMedicine. …
Bone loss drugs may help prevent endometrial cancer
Endometrial cancer, which arises in the lining of the uterus, accounts for nearly 50 percent of gynecologic cancers diagnosed in the United States, and it is the fourth most common malignancy in women and the eighth most common cause of cancer death. …
Suppressing a protein reduces cancer spread in mice
“We think everybody has Chitinase 3-like-1 (CHI3L1) in them because it plays a major role in our ability to fight off infections,” said Dr. Jack A…
Neuro-oncologists discover cancer cells can burn acetate for fuel
Researchers have been struggling with what fuels cancer cell growth. For more than 75 years, researchers have known that cancer cells use glucose as the major fuel, but efforts to halt cancer growth by controlling glucose levels in the brain haven’t worked…
Cells identified that enhance tumor growth and suppress anti-cancer immune attack
For years, researchers have known that a diverse group of white blood cells called myeloid-derived suppressor cells (MDSC) are more abundant in cancer patients than in healthy individuals. The cells enhance cancer growth and suppress the specialized T cells that target and destroy tumor cells…
Researchers hope patent can pave way to future treatments of heart, lung disease
The team’s ongoing work may have far-reaching implications, including new ways to treat tissue damaged during a heart attack or stroke, and even a possible cure for cancer. U.S…
How does prostate cancer form? Parkinson’s Link? — ScienceDaily
“Using genetic deletion we found that SIRT1 normally restrains prostatic intraepithelial neoplasia in animals. …
Life expectancy increases globally as death toll falls from major diseases
Causes of death vary widely by country, but, at the global level, drug use disorders and chronic kidney disease account for some of the largest percent increases in premature deaths since 1990. Death rates from some cancers, including pancreatic cancer and kidney cancer, also increased. …