Tag Archives: stephen

New discovery approach accelerates identification of potential cancer treatments

They used the platform to identify a novel antibody that is undergoing further investigation as a potential treatment for breast, ovarian and other cancers. In research published online in the Proceedings of the National Academy of Sciences, researchers in the lab of Stephen Weiss at the U-M Life Sciences Institute detail an approach that replicates the native environment of cancer cells and increases the likelihood that drugs effective against the growth of tumor cells in test tube models will also stop cancer from growing in humans. The researchers have used their method to identify an antibody that stops breast cancer tumor growth in animal models, and they are investigating the antibody as a potential treatment in humans. “Discovering new targets for cancer therapeutics is a long and tedious undertaking, and identifying and developing a potential drug to specifically hit that target without harming healthy cells is a daunting task,” Weiss said. …

New discovery approach accelerates identification of potential cancer treatments — ScienceDaily

They used the platform to identify a novel antibody that is undergoing further investigation as a potential treatment for breast, ovarian and other cancers. In research published online in the Proceedings of the National Academy of Sciences, researchers in the lab of Stephen Weiss at the U-M Life Sciences Institute detail an approach that replicates the native environment of cancer cells and increases the likelihood that drugs effective against the growth of tumor cells in test tube models will also stop cancer from growing in humans. The researchers have used their method to identify an antibody that stops breast cancer tumor growth in animal models, and they are investigating the antibody as a potential treatment in humans. …

Scientists make advance in cancer research

The most advanced version of vβ3-integrin antagonists failed clinical trials to treat aggressive forms of brain cancer. But research published today in the American Heart Association’s journal Circulation Research shows that targeting the protein in question could still be vital in stopping the growth of tumors. Not least because the drugs targeting it cause minimal side effects compared to other drugs — which can cause bleeding in the gut and high blood pressure. tumors must recruit their own blood supply to grow beyond a very small size…

Judge orders second child be put on adult waiting list for donated lungs

PHILADELPHIA – & A federal judge has ordered that a second child at a Philadelphia hospital -- a New York City boy -- be put on the adult waiting list for donated lungs. The ruling from U.S. District Judge Michael Baylson involves 11-year-old Javier Acosta of the Bronx, who has cystic fibrosis. His mother filed a lawsuit Thursday that says he will die soon unless he gets a lung transplant. The decision comes a day after a national organ transplant network complied with Baylson's unusual order to place a dying 10-year-old girl on the list. Children under 12 are currently matched with pediatric donors, which are rare, or wait at the end of the adult list. Medical ethicists question the judge's intervention. But lawyer Stephen Harvey, who represents both families, fears that Javier and Sarah will die while the issue is reviewed.source : http://www.foxnews.com/health/2013/06/06/judge-orders-second-child-be-put-on-adult-waiting-list-for-donated-lungs/

Man brought back to life after being clinically dead for 40 minutes

An Australian man who was clinically dead for 40 minutes has been brought back to life by a brand new resuscitation technique. Colin Fiedler, 39 from Victoria, was one of three cardiac arrest patients brought back to life after being dead for between 40 and 60 minutes at The Alfred hospital in Melbourne, using two new techniques in the emergency department. The Alfred is testing a mechanical CPR machine, which performs constant chest compressions, and a portable heart-lung machine -- normally used in theatre -- to keep oxygen and blood flowing to the patient's brain and vital organs. Fiedler had a heart attack and was clinically dead for 40 minutes before being revived last June. “I'm so grateful, more than I could ever say,” he told the Herald Sun. So far, seven cardiac arrest patients have been treated with the AutoPulse machine and extracorporeal membrane oxygenation. It allows doctors to diagnose the cause of the cardiac arrest and treat it, but keep blood and oxygen flowing to the vital organs and brain, which reduces the risk of permanent disability. Fiedler is one of the three patients who were revived and returned home without disability. In the ambulance, paramedics had given him a choice of two hospitals. “For some reason, I said The Alfred, which is pretty lucky, because they are the only one that has it,” he said. The system is available only at The Alfred, but senior intensive care physician Professor Stephen Bernard said the results from the first two years of the trial were exciting, and he hopes to eventually expand the system across Melbourne. Click for more from news.com.au.source : http://www.foxnews.com/health/2013/05/13/man-brought-back-to-life-after-being-clinically-dead-for-40-minutes/