Scientists pinpoint protein that could improve small cell lung cancer therapies — ScienceDaily
source : http://www.sciencedaily.com/releases/2014/04/140422152819.htm
Tag Archives: sclc
Investigational PARP inhibitor promising in BRCA-related cancers
When there is damage to DNA in human cells, two proteins, PARP 1 and 2, recruit proteins that can repair the damage associated with loss of BRCA proteins. Mutations in BRCA genes often result in inefficient repair of damaged DNA, which increases the risk for developing certain cancers, including cancers of the breast and ovary. Inhibiting PARP, therefore, prevents the repair of damaged DNA, leading to cell death. …