Some research, including animal studies, has suggested that dietary nutrients can have an effect on the onset and progression of cataracts. Vitamin E and selenium are of particular interest…
The study, led by Johns Hopkins Kimmel Cancer Center researchers, shows how in principle, radiation may specifically activate immune system cells responsible for attacking cancer cells, leading immune cells to “remember” how to fight cancer long after the cancer is gone. Andrew Sharabi, M.D., Ph.D., a resident in the Department of Radiation Oncology and Molecular Radiation Science at Johns Hopkins, is expected to present details of the study at the 2014 annual meeting of the American Society of Radiation Oncology (ASTRO) in San Francisco Sept. 15…
“For the first time, we have established that the genes controlling the length of these telomeres play a part in the risk of developing melanoma,” said lead author of the study Mark Iles, PhD, School of Medicine at the University of Leeds (UK). Telomeres are a part of the genome that function like the plastic caps of your shoelaces, which prevent the laces from fraying…
The study, using a national database of more than 100,000 women treated during the last decade, found that today nationally radiation oncologists are less likely to use radiotherapy in women older than 70 with early-stage estrogen-receptor-positive breast cancer and that when they do, treatment is appropriately less-intensive. This follows a randomized trial demonstrating low rates of recurrence in women who don’t receive radiotherapy after lumpectomy, provided they take endocrine therapy. This confirms radiation oncologists are responding to a growing impetus to keep medical practices current and cost-effective, said first author Charles Rutter, M.D., a radiation oncology resident in Yale’s School of Medicine. …
The study, using a national database of more than 100,000 women treated during the last decade, found that today nationally radiation oncologists are less likely to use radiotherapy in women older than 70 with early-stage estrogen-receptor-positive breast cancer and that when they do, treatment is appropriately less-intensive. This follows a randomized trial demonstrating low rates of recurrence in women who don’t receive radiotherapy after lumpectomy, provided they take endocrine therapy. This confirms radiation oncologists are responding to a growing impetus to keep medical practices current and cost-effective, said first author Charles Rutter, M.D., a radiation oncology resident in Yale’s School of Medicine. “In light of the current environment surrounding the cost of healthcare — with an intense focus on costs — only treatments with meaningful benefit should be delivered,” Rutter said…
The original NSABP B-32 study was a randomized trial of sentinel node biopsy (SNB) versus SNB + axillary lymph node dissection (ALND) in 5,611 women with clinically node-negative breast cancer. The study was initiated to determine if SNB was as effective as ALND with fewer side effects. Although designed to assess the impact of type of axillary surgery specifically on lymphedema risk, the NSABP B-32 trial also provided the opportunity to evaluate the impact of radiation therapy (RT) on lymphedema risk. …
Now for the first time, a new study published in the September 2014 Journal of the National Cancer Institute (JNCI) and led by Brian Sprague, Ph.D., a University of Vermont assistant professor of surgery and member of the Vermont Cancer Center, estimates the number of women in the United States for whom breast density notification legislation would potentially impact. The study was conducted with the National Breast Cancer Surveillance Consortium and utilizes data from breast cancer screening registries based at the University of Vermont, the Group Health Research Institute (Seattle, WA), the University of North Carolina, Dartmouth’s Geisel School of Medicine, the University of California-San Francisco, and the University of New Mexico. Given their findings, Sprague and his research team are asking policy makers to consider the large number of women who fall into the category of having mammographically-dense breasts in the U.S…
Now for the first time, a new study published in the September 2014 Journal of the National Cancer Institute (JNCI) and led by Brian Sprague, Ph.D., a University of Vermont assistant professor of surgery and member of the Vermont Cancer Center, estimates the number of women in the United States for whom breast density notification legislation would potentially impact. The study was conducted with the National Breast Cancer Surveillance Consortium and utilizes data from breast cancer screening registries based at the University of Vermont, the Group Health Research Institute (Seattle, WA), the University of North Carolina, Dartmouth’s Geisel School of Medicine, the University of California-San Francisco, and the University of New Mexico. Given their findings, Sprague and his research team are asking policy makers to consider the large number of women who fall into the category of having mammographically-dense breasts in the U.S. as they debate breast density notification legislation and screening recommendations…
Researchers evaluated clinical features and survival outcomes among 41,502 patients diagnosed with stage I and II Hodgkin’s Disease from 1998 to 2011 from a prospectively collected database — the National Cancer Data Base (NCDB), which is composed of cases from 1,500 sites and represents >75 percent of all cancers diagnosed in the U.S. The average patient age was 37 (range: 18 — 90), with a median follow-up of 7.5 years. The association between RT use, co-variables and outcome were assessed in a multivariate Cox proportional hazards model…
ALL is the most common childhood cancer. The research focused on a subtype of ALL known as Philadelphia chromosome-like ALL (Ph-like ALL)…