Tag Archives: sandra

Pertuzumab adds 16 months survival benefit to trastuzumab and chemotherapy treatment for HER2-positive metastatic breast cancer — ScienceDaily

CLEOPATRA was a pivotal phase III study where researchers evaluated the safety and efficacy of pertuzumab, trastuzumb and chemotherapy in 808 patients with previously untreated HER2-positive metastatic breast cancer. HER2-positive metastatic breast cancer has historically been one of the most aggressive forms of the disease. “In CLEOPATRA we evaluated whether dual HER2 blockade by combining the antibody pertuzumab with trastuzumab and chemotherapy would help people live longer (overall survival, OS) or live longer without their disease worsening (progression-free survival, PFS),” explains lead author Dr Sandra Swain from Washington Hospital Center, Washington, USA…

New function of two molecules involved in metastasis

Transcription factors are proteins that regulate gene expression. They activate or deactivate a gene’s function. Researchers at IMIM have studied the function of one of these transcription factors, Snail1, in mouse cells during the Epithelial-Mesenchymal Transition (EMT). Sandra Peiró, a researcher from the IMIM Research Group on Epithelial-Mesenchymal Transition and Tumor Progression explains: "EMT is a process consisting of converting epithelial cells, the ones covering the internal and external surfaces of the body, into what are known as mesenchymal cells. …

Washington baby bitten by bat treated for rabies

PASCO, Wash. – & A baby is being treated for rabies after it was bitten by a bat that flew out of a patio umbrella on the deck of her grandparents' Pasco home, the Tri-City Herald reported. Dan and Sandra Anderson were babysitting 11-month-old Alanna on Saturday evening when Dan Anderson opened the umbrella and Sandra Anderson noticed something flutter out toward Alanna. “It was weird. I thought maybe it was moths,” Sandra Anderson said. Then she saw the bat clinging to Alanna's back near her left shoulder. She brushed the bat away and then noticed two pair of tiny bite marks, even though the bat had been on the baby only a few seconds. Alanna didn't cry — until she noticed how upset her grandmother was. The baby was given shots at Kadlec Regional Medical Center in Richland. Her grandparents are getting vaccine shots for rabies, too, as a precaution. The family thought it had seen the last of the bat, but they were on the patio again Sunday for Mother's Day when they noticed something black inside the closed umbrella. This time, Alanna's father, Derek Anderson, killed it with a piece of metal. He turned it over to the Benton Franklin Health Department and it tested positive for rabies. The virus can be fatal without medical attention. “I'm thankful we saw the bat on her and could take her for treatment,” said Sandra Anderson. “Everything's fine. It's 100 percent curable,” Derek Anderson said.source : http://www.foxnews.com/health/2013/05/15/washington-baby-bitten-by-bat-treated-for-rabies/