Tag Archives: research

Breast cancer recurrence: Study provides insight

Around 5,000 cases of DCIS, a condition where cancerous cells are contained within the milk ducts of the breast, are diagnosed each year in the UK, with two thirds diagnosed through breast screening. If left untreated, up to half of DCIS cases could progress into invasive breast cancer, but it is not possible to say which ones, so all women are offered treatment. This usually involves breast-conserving surgery (lumpectomy) and, to reduce the risk of the cancer returning, radiotherapy to kill any remaining cancer cells. However, even with treatment up to one in five patients will see their DCIS come back, either as DCIS or as invasive breast cancer. …

Synthetic lethality offers new approach to kill tumor cells, explains researcher — ScienceDaily

“Genetic alterations in cancer in humans may involve gene inactivation, amplification or inactivation,” said List.These changes are not present in nonmalignant cells. Common chemotherapeutic agents aggressively kill tumor cells irrespective of genetic alterations.They also have a negative impact on normal cells and can cause significant side effects. …

Sea sponge drug could boost advanced breast cancer survival by five extra months — ScienceDaily

Researchers led by Professor Chris Twelves, based at the University of Leeds and Leeds Teaching Hospitals NHS Trust, looked at two major clinical trials of more than 1,800 women with breast cancer that had started to spread to other parts of the body. The phase III trials — the final stage of testing before deciding whether a drug can be prescribed to patients — compared the survival of women treated with eribulin to those given standard treatment…

Clear new evidence for mind-body connection demonstrated in study — ScienceDaily

A group working out of Alberta Health Services’ Tom Baker Cancer Centre and the University of Calgary Department of Oncology has demonstrated that telomeres — protein complexes at the end of chromosomes — maintain their length in breast cancer survivors who practise meditation or are involved in support groups, while they shorten in a comparison group without any intervention. Although the disease-regulating properties of telomeres aren’t fully understood, shortened telomeres are associated with several disease states, as well as cell aging, while longer telomeres are thought to be protective against disease. “We already know that psychosocial interventions like mindfulness meditation will help you feel better mentally, but now for the first time we have evidence that they can also influence key aspects of your biology,” says Dr. Linda E. …

‘Invisible tattoos’ could improve body confidence after breast cancer radiotherapy — ScienceDaily

Research suggests that the permanent pin prick marks made on the skin of women having radiotherapy reminds them of their diagnosis for years to come, reducing body confidence and self-esteem. It’s also more difficult to spot these tattoos in dark-skinned women, potentially leading to inconsistencies in the area being treated. The NIHR-funded researchers, based at The Royal Marsden hospital in London, asked 42 breast cancer patients undergoing radiotherapy to rate how they felt about their body, before the treatment and one month later. Half the women were offered fluorescent tattoos, only visible under UV light, while the other half had conventional dark ink tattoos. …

Ethnic minorities less aware of cancer symptoms, more likely to identify barriers to seeking medical help

Researchers looked at nearly 50,000 responses to the Cancer Research UK Cancer Awareness Measure from people across England. They found that ethnic minority groups were consistently less aware of cancer symptoms. People with a black ethnic background were half as likely as white people to recognise that unexplained bleeding could be a symptom of cancer; while South Asians were a quarter as likely as white people to recognise that an unexplained lump or swelling could be a cancer symptom…

‘Invisible tattoos’ could improve body confidence after breast cancer radiotherapy

Research suggests that the permanent pin prick marks made on the skin of women having radiotherapy reminds them of their diagnosis for years to come, reducing body confidence and self-esteem. It’s also more difficult to spot these tattoos in dark-skinned women, potentially leading to inconsistencies in the area being treated…

Step towards blood test for many cancer types

This is the first time that cancer-specific blood markers have been comprehensively reviewed and identified for further clinical development. This study, by the UK Early Cancer Detection Consortium, funded by Cancer Research UK, has analysed 19,000 scientific papers and found more than 800 biomarkers. The aim of this research is to develop a screening test from a single blood sample for multiple cancer types. All cancers produce markers in the blood, so it could be feasible to develop a general screening test for many different forms of the disease. …