Key protein behind aggressive forms of endometrial cancer — ScienceDaily
source : http://www.sciencedaily.com/releases/2014/05/140505211242.htm
source : http://www.sciencedaily.com/releases/2014/05/140505211242.htm
source : http://www.sciencedaily.com/releases/2014/05/140504182212.htm
source : http://www.sciencedaily.com/releases/2014/02/140224171145.htm
A new study from researchers at the University of Michigan Comprehensive Cancer Center found that these cells, called myeloid derived suppressor cells, provide a niche where the cancer stem cells survive. …
A University of Colorado Cancer Center study published in the journal PLoS One explores two of these low-molecular-weight (LMW) PAHs — 1-methylanthracene (1-MeA) and 2-methylanthracene (2-MeA) — and shows that while they don’t necessarily cause cancer, 1-MeA promotes conditions that will likely allow cancer to grow. "There’s a big distinction between initiating cancer and promoting it," says Alison Bauer, PhD, CU Cancer Center investigator and assistant professor at the Colorado School of Public Health. Her study showed that in a mouse cell model using a progenitor cell of lung cancer, the LMW 1-MeA promoted inflammation and increased mitogenic pathways, both of which are linked to tumor promotion. 2-MeA, while nearly structurally identical, did not…