But researchers at UT Southwestern Medical Center and Karolinska Institutet in Stockholm, Sweden, found that endogenous retroviruses (ERV) also play a critical role in the body’s immune defense against common bacterial and viral pathogens. “Most scientists have become used to the view that retroviruses are generally harmful,” said Nobel Laureate Dr. …
The review highlights that menopausal symptoms, including hot flushes and night sweats are common, affecting around 70% of women for an average of 5 years but may continue for many years in about 10% of women. Every woman experiences the menopause differently; some experience one or two symptoms mildly while others have more severe symptoms. …
For years, researchers have known that a diverse group of white blood cells called myeloid-derived suppressor cells (MDSC) are more abundant in cancer patients than in healthy individuals. The cells enhance cancer growth and suppress the specialized T cells that target and destroy tumor cells…
Open radical cystectomy, or removal of the bladder though open surgery, is the treatment of choice for muscle invasive and high-risk non-muscle invasive bladder cancer; however, the surgery can lead to serious complications. Some hospitals are using minimally invasive procedures such as laparoscopic radical cystectomy, but there is little information on the effectiveness of these procedures for preventing cancer recurrence over the long term…
“Using genetic deletion we found that SIRT1 normally restrains prostatic intraepithelial neoplasia in animals. Therefore too little SIRT1 may be involved in the cellular processes that starts human prostate cancer,” said Dr. Richard Pestell, M.D., Ph.D., MBA, executive Vice President of Thomas Jefferson University and Director of the Sidney Kimmel Cancer Center. “As we had shown that gene therapy based re expression of SIRT1 can block human prostate cancer tumor growth, and SIRT1 is an enzyme which can be targeted, this may be an important new target for prostate cancer prevention.” The researchers led by Dr…
The scientists started analyzing samples of human mantle cell lymphoma in a bid to find errors in the DNA. They discovered a region that is mutated in almost 30 percent of patients…
The study – funded by Cancer Research UK, Action Medical Research and others – shows that taking an extra tumour sample at recurrence, when there are no effective therapies, could identify subsets of patients that might be treatable with existing drugs that target the genetic faults. …
The team’s ongoing work may have far-reaching implications, including new ways to treat tissue damaged during a heart attack or stroke, and even a possible cure for cancer. U.S…
Airplane windshields are commonly made of polycarbonate plastic or multilayer composite glass. UV-A radiation can cause DNA damage in cells and its role in melanoma is well known, according to the article. Author Martina Sanlorenzo, M.D., of the University of California, San Francisco, and co-authors measured the amount of UV radiation in airplane cockpits during flights and compared them with measurements taken in tanning beds. The cockpit radiation was measured in the pilot seat of a general aviation turboprop airplane through the acrylic plastic windshield at ground level and at various heights above sea level…
MPM is a fatal cancer associated with asbestos exposure that develops on the outer linings of the lungs. The 3-year survival rate is only 8% and most MPM patients are diagnosed with late stage disease with limited therapeutic options…