Tag Archives: paclitaxel

To sleep, perchance to dream of a cure

And once the sleep was lost, there was no getting its positive effect back by allowing extra rest later. In “Recovery Sleep Does Not Mitigate the Effects of Prior Sleep Loss on Paclitaxel-Induced Mechanical Hypersensitivity in Sprague-Dawley Rats,” a preclinical study published in Biological Research for Nursing, restricted sleep among rats led to worse reactions to PAC, associated with painful, debilitating peripheral neuropathy of the hands and feet that may persist long after therapy is completed. According to the study, “How poor sleep sets the stage for adverse outcomes among people diagnosed with cancer is not entirely understood…