Although the results were derived from a large nationwide cohort study, the investigators emphasise that the findings should next be replicated in further studies and that presently there is no reason for earlier breast cancer screening than is recommended for the general population. …
Efforts to make this treatment possible have been limited by a dearth of insulin-producing beta cells that can be removed from donors after death, and by the stubborn refusal of human beta cells to proliferate in the laboratory after harvesting. The new technique uses a cell conditioning solution originally developed to trigger reproduction of cells from the lining of the intestine. "Until now, there didn’t seem to be a way to reliably make the limited supply of human beta cells proliferate in the laboratory and remain functional," said Michael McDaniel, PhD, professor of pathology and immunology…
There's an unexpected link between marijuana use and factors related to Type 2 diabetes that has medical researchers intrigued. Several studies have found that marijuana users take in more food calories than nonusers, but they still have lower rates of obesity and diabetes, and lower average body mass index (BMI) levels. In a new study, researchers investigated what effects marijuana and its active ingredient tetrahydrocannabinol (THC) might have on people's metabolism, especially insulin levels. [5 Diets That Fight Diseases] Insulin resistance an important risk factor for diabetes is a metabolic disorder that occurs when the body's cells cannot properly intake insulin. The American Heart Association estimates 35 percent of U.S. adults have metabolic disorders that include insulin resistance. To examine the link between THC and metabolism, researchers gathered the results of 4,657 adults from the National Health and Nutrition Examination Survey, a cross-sectional study administered annually by the Centers for Disease Control and Prevention. Of the study's participants, 579 were current marijuana users, 1,975 had used the drug in the past but not recently, and 2,103 had never tried marijuana. Researchers analyzed the participants' fasting insulin levels, cholesterol levels, insulin resistance and waist sizes. Multiple benefits seen The results showed that the current marijuana users had 16 percent lower fasting insulin levels than nonusers, and 17 percent lower insulin-resistance levels. Additionally, the regular users of marijuana had smaller average waist sizes, and higher levels of high-density lipoprotein (HDL) cholesterol, aka “good cholesterol.” “These are indeed remarkable observations that are supported by basic science experiments that came to similar conclusions,” Dr. Joseph Alpert, professor of medicine at the University of Arizona College of Medicine, Tucson, said in a statement. Interestingly, only the current users of marijuana (not the former users) experienced the positive results, suggesting that the effects of marijuana use on insulin and insulin resistance only occur after recent use. To test their results, which were published in the latest issue of The American Journal of Medicine, the researchers also adjusted for participants who had been diagnosed with Type 2 diabetes. Much more research needed “After we excluded those subjects with a diagnosis of diabetes the associations between marijuana use and insulin levels, [insulin resistance], waist circumference and HDL-C were similar and remained statistically significant,” Dr. Elizabeth Penner, a co-author of the study, said in a statement. “Is it possible that THC will be commonly prescribed in the future for patients with diabetes or metabolic syndrome alongside antidiabetic oral agents or insulin for improved management of this chronic illness? Only time will answer this question for us,” Alpert said in an editorial accompanying the article in the journal. “We desperately need a great deal more basic and clinical research into the short- and long-term effects of marijuana in a variety of clinical settings such as cancer, diabetes and frailty of the elderly,” Alpert wrote. Copyright 2013 LiveScience, a TechMediaNetwork company. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.source : http://www.foxnews.com/health/2013/05/16/could-marijuana-reduce-diabetes-risk/
The findings are published in this week’s online Early Edition of the Proceedings of the National Academy of Sciences. Roughly 90 percent of all cancer deaths are due to metastasis — the disease spreading from the original tumor site to multiple, distant tissues and finally overwhelming the patient’s body. Lymph vessels are often the path of transmission, with circulating tumor cells lodging in the lymph nodes — organs distributed throughout the body that act as immune system garrisons and traps for pathogens and foreign particles. The researchers, led by principal investigator Judith A. …