Protein found to block benefits of vitamin A cancer therapy
Details of the study were published this week in the online edition of the journal Cancer Research, a journal of the American Association for Cancer Research. …
Details of the study were published this week in the online edition of the journal Cancer Research, a journal of the American Association for Cancer Research. …
source : http://www.sciencedaily.com/releases/2014/05/140501112325.htm
source : http://www.sciencedaily.com/releases/2014/02/140203191835.htm
"It is still too premature to estimate when a clinical trial will open to further test this drug combination therapy, but we are now in the planning phase and encouraged by the results of these laboratory experiments," says Andrew Poklepovic, M.D., oncologist and member of the Developmental Therapeutics research program at VCU Massey Cancer Center and assistant professor in the Division of Hematology, Oncology and Palliative Care at VCU School of Medicine. …
The identification of CPTP was the result of an international collaboration that built on prior research by co-lead author Charles Chalfant, Ph.D., Endowed Chair of Cancer Cell Signaling and member of the Cancer Cell Signaling program at Virginia Commonwealth University Massey Cancer Center as well as professor in the Department of Biochemistry and Molecular Biology at VCU School of Medicine. The team discovered that CPTP regulates levels of biologically active lipids, which are molecules such as fatty acids that often play a role in cell signaling…