Professor Wayne Brodland is developing computational models for studying the mechanical interactions between cells. In this project, he worked with a team of international researchers who found that the way wounds knit together is more complex than we thought…
This achievement sets the stage to use x-ray crystallography to develop complete images of HIV that include integrase, which in turn will help scientists develop new treatments for the illness. Duane Grandgenett, Ph.D., professor at SLU’s Institute of Molecular Virology and senior author of the study, discovered integrase in 1978, little knowing the piece of virus would provide the basis for an entire class of drugs that now treats HIV…
“The prostate cancer risk calculator has been updated using current risk factors and a better interface; the current version gives a more nuanced result that helps understand a man’s risk of prostate cancer,” said Ian M. …
“The prostate cancer risk calculator has been updated using current risk factors and a better interface; the current version gives a more nuanced result that helps understand a man’s risk of prostate cancer,” said Ian M. Thompson Jr., M.D., director of the Cancer Therapy & Research Center at the UT Health Science Center, who helped develop the risk calculator and co-authored a commentary published today in the Journal of the American Medical Association. The free calculator on the Health Science Center website takes just minutes to use and gives a man more information about his risk for both low-grade prostate cancer, which may never require treatment, and high-grade prostate cancer. It provides an “emoji” graphic readout that puts the numeric percentages into a visual perspective. …
Researchers from the University of Texas at Austin’s Cockrell School of Engineering have now developed a probe that combines into one device three unique ways of using light to measure the properties of skin tissue and detect cancer. The researchers have begun testing their 3-in-1 device in pilot clinical trials and are partnering with funding agencies and start-up companies to help bring the device to dermatologists’ offices. The researchers describe the skin cancer probe in a new paper published in the journal Review of Scientific Instruments, from AIP Publishing. Skin cancers of all types are the most common forms of cancer in North America, and melanoma, the most deadly form of skin cancer, is one of the leading causes of cancer death, killing nearly 10,000 people every year in the United States. …
Using data from a previously published, multi-center study funded by the National Cancer Institute, researchers aimed to identify the possible benefits of assigning patient navigators to women recently diagnosed with breast cancer. According to the results, women were more likely to start recommended treatment when assisted by one of these trained specialists. For example, they were more likely to start hormonal therapy, which is considered the gold standard in treatment for certain types of breast cancer. Naomi Ko, MD, MPH, instructor of medicine in the Section of Hematology Oncology at Boston University School of Medicine and a practicing breast oncologist at Boston Medical Center, stresses the need for further investigation…
“This fascinating new finding could help doctors adapt their treatments to patients with bladder cancer,” said Nell Barrie, Cancer Research UK The team from The University of Manchester, funded by the Medical Research Council, found that patients whose bladder tumor had high levels of a protein, called ‘HIF-1α’, were more likely to benefit from having carbogen — oxygen mixed with carbon dioxide gas — and nicotinamide tablets at the same time as their radiotherapy. The treatment, called ‘CON’, makes radiotherapy more effective. By comparing levels of HIF-1α in tissue samples from 137 patients who had radiotherapy on its own or with CON, the researchers found the protein predicted which patients benefited from having CON. High levels of the protein were linked to better survival from the disease when patients had radiotherapy and CON. …
Researchers from the University of São Paulo (USP) have identified an RNA known as INXS that, although containing no instructions for the production of a protein, modulates the action of an important gene in the process of apoptosis, or programmed cell death. …
The researchers found that retinoblastoma protein (RB), a protein known to reduce cancer risk, is significantly less active in male brain cells than in female brain cells. The study appears Aug. …
These results conflict with a recent study published in BMJ’s Journal of Epidemiology and Community Health suggesting that seven or more daily portions of fruits and vegetables were linked to lowest risk of death. There is growing evidence that increasing fruit and vegetable consumption is related to a lower risk of death from cardiovascular disease and cancer. However, the results are not entirely consistent. …