Tag Archives: idibell

New potential therapeutic strategy against a very aggressive infant bone cancer

Ewing’s Sarcoma Ewing’s sarcoma is the second most common bone cancer and affects children and adolescents. Currently, if diagnosed in time and there is no metastasis, it can be cured in 80% of cases but between 25% and 30% of cases are diagnosed when there is already metastasized, at which low survival to 30 %. The study published in Cancer Research demonstrates that overexpression of the protein sirtuin 1 very significantly correlated with metastasis in patient samples Ewing Sarcoma. …

Dog’s epigenome gives clues to human cancer

Unlike other mammals used in research, dogs develop cancer spontaneously as humans do and cancer is the most common cause of death in this species. The dog genome has been obtained in recent years, but we still don’t know how is controlled and regulated, what we call the epigenome. This week the team led by Manel Esteller, director of the Program for Epigenetics and Cancer Biology (PEBC) at Bellvitge Biomedical Research Institute (IDIBELL), Professor of Genetics at the University of Barcelona and ICREA researcher, has characterized the dog’s epigenome and transferred the results to human cancer to understand the changes in appearance of tumors. The finding is published this week in the journal Cancer Research. …