"I think that most organic chemists had considered ingenol beyond the reach of scalable chemical synthesis," said TSRI Professor Phil S. Baran. Baran and his laboratory report their achievement in this week’s issue of Science Express, the early online edition of the journal Science…
"Understanding this previously ignored part of the human genome, its role in human development, and how it may be taken over by disease, opens a new frontier in science with important implications for medical advances," said Philipp Kapranov, Ph.D., lead researcher at the St. …
"This is a proof of concept study using human cells," said Sergei Rudchenko, Ph.D., director of flow cytometry at Hospital for Special Surgery (HSS) in New York City and a senior author of the study. …
Height was linked to cancers of the breast, colon, endometrium, kidney, ovary, rectum, and thyroid, as well as to multiple myeloma and melanoma, and these associations did not change even after adjusting for factors known to influence these cancers, in this study of 20,928 postmenopausal women, identified from a large cohort of 144,701 women recruited to the Women’s Health Initiative (WHI). "We were surprised at the number of cancer sites that were positively associated with height…
This finding, published in Cancer Research, a journal of the American Association for Cancer Research (AACR), may be used to develop therapeutic treatments for patients. "Our research has shown that HGMA2 plays a part in regulating the spread of cancer and could be considered a driver of the process," said Dr. Chada, who was principal investigator of the study. "Further studies could result in the development of therapeutic treatments for patients with breast cancer which could prevent HGMA2’s function, reduce the spread of cancer and extend a patient’s life." According to Dr…
HPV has been linked to anal, penile and certain types of throat cancers in men. Since the virus is also responsible for various cancers in women, vaccinating boys will play a crucial role in reducing cancer rates across the sexes. "HPV is the single most common sexually transmitted infection," says Newman, Canada Research Chair in Health and Social Justice. …
Myc acts somewhat like a master switch within cells to foster uncontrolled growth. …
Scientists working to develop new drugs and vaccines hope to target the parasite in the earliest stages of an infection, when it quietly reproduces itself in the human liver. In a major step toward that goal, a team led by MIT researchers has now developed a way to grow liver tissue that can support the liver stage of the life cycle of the two most common species of malaria, Plasmodium falciparum and Plasmodium vivax. This system could be used to test drugs and vaccines against both species, says Sangeeta Bhatia, the John and Dorothy Wilson Professor of Health Sciences and Technology and Electrical Engineering and Computer Science at MIT. …
Now it seems each week yields important new discoveries about the deadly skin cancer. "I’ve been doing this for 30 years, and now is by any measure the most exciting time for melanoma research," said Brian Nickoloff, director of the Nicholas V. Perricone, M.D., Division of Dermatology and Cutaneous Sciences at Michigan State University’s College of Human Medicine. …
In rodents, intestinal bacteria influence obesity, intestinal inflammation, and certain types of epithelial cancers. …