Led by Professor Jean Paul Thiery, Senior Principal Investigator, and Dr Ruby Huang, Principal Associate, both from CSI Singapore, the scientists developed a scoring scheme which monitors the epithelial-mesenchymal transition (EMT) mechanism. This process was shown to play a role in a large number of cancer-related events, including cancer invasion, metastasis, and chemo-resistance…
Results of the study were presented today at the annual meeting of ESHRE by Dr Carrie Williams from the Institute of Child Health, University College London, UK. This was a large population-based linkage study between the Human Fertilisation & Embryology Authority (HFEA, the UK’s regulatory authority for ART clinics) and the UK’s National Registry of Childhood Tumours (NRCT).(1) The HFEA records of all 106,381 children born after assisted conception in the UK from 1992 to 2008 were linked to NRCT records to calculate the number of children who subsequently developed cancer. Once the databases were linked, cancer rates in the ART cohort were compared with population rates, whilst stratifying for potential mediating factors including birth weight, multiple births, treatment type and infertility cause. …