Tag Archives: current

New weapon in fight against cervical cancer

The E7 protein is produced early in the lifecycle of the human papillomavirus (HPV) and blocks the body’s natural defences against the uncontrolled division of cells that can lead to cancer. Researchers at the University of Leeds’ School of Molecular and Cellular Biology have synthesised a molecule, called an RNA aptamer, that latches onto the carcinogenic protein and targets it for destruction, significantly reducing its presence in cells in the laboratory derived from cervical cancers…

Simple vision test may predict IQ

A simple visual test is surprisingly accurate at predicting IQ, according to new research. The study, published May 23 in the journal Current Biology, found that people's ability to efficiently filter out visual information in the background and focus on the foreground is strongly linked to IQ. The findings could help scientists identify the brain processes responsible for intelligence. That doesn't mean snappy, efficient visual processing leads to smarts, said study co-author Duje Tadin, a neuroscientist at the University of Rochester in New York. Instead, common brain processes may underlie both intelligence and efficient visual processing. IQ hunting Since the 1800s, the forefathers of IQ testing, including Sir Francis Galton (who also pioneered the science of fingerprinting), suspected that highly intelligent people also have supersensory discrimination. But studies in the subsequent decades have found only a modest connection between IQ-test scores and peoples ability to quickly or accurately spot motion in images. Tadin and his colleagues were studying a separate question on visual perception in 12 participants when they found something striking: IQ seemed to be correlated strongly with performance on a visual task. The test asked users to spot the direction of motion on a series of black-and-white stripes on a screen. Sometimes, the lines formed inside a small central circle, and other times, they were large stripes that took up the entire screen. Participants also completed a short IQ test. [Watch Video of Motion and Test Your Smarts] The team noticed that people with higher IQs were good at spotting motion in the small circles, but terrible at detecting motion in the larger black-and-white stripes. Because they had looked at so few people, Tadin and his colleagues wondered if their results were a fluke. They repeated the experiment with 53 people, who also took a full IQ test. The ability to visually filter the motion strongly predicted IQ in fact, motion suppression (the ability to focus on the action and ignore background movements) was as predictive of total IQ as individual subsections of the IQ test itself. Relevant information As people walk, the background scenery is always changing, so efficient brains may be better at filtering out this irrelevant visual information. And that efficiency could be operating across a wide range of tasks, Tadin said. “What happens in brains of high-IQ people is, they're automatically processing motion of small moving objects efficiently, whereas they're suppressing the background,” Tadin said. The findings reshape the conventional view that quick thinking leads to smarts. “Speedy processing does matter, but it's only half the story. It's how you filter out things that are less relevant and focus your speedy resources on what is important,” Tadin said. Big variation The study reveals new insights into brain efficiency and smarts, said Kevin McGrew, director of the Institute for Applied Psychometrics and owner of www.themindhub.com. Even though the link between IQ and visual filtering was very strong, IQ tests won't be replaced by motion tracking anytime soon, said McGrew, who was not involved in the study. “Their task accounts for or explains about 50 percent of the IQ scores,” McGrew told LiveScience. “That is impressive in psychology, but it still means there is 50 percent of the scores that they're not explaining.” Copyright 2013 LiveScience, a TechMediaNetwork company. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.source : http://www.foxnews.com/health/2013/05/24/simple-vision-test-predicts-iq/

Simple vision test may predicts IQ

A simple visual test is surprisingly accurate at predicting IQ, according to new research. The study, published May 23 in the journal Current Biology, found that people's ability to efficiently filter out visual information in the background and focus on the foreground is strongly linked to IQ. The findings could help scientists identify the brain processes responsible for intelligence. That doesn't mean snappy, efficient visual processing leads to smarts, said study co-author Duje Tadin, a neuroscientist at the University of Rochester in New York. Instead, common brain processes may underlie both intelligence and efficient visual processing. IQ hunting Since the 1800s, the forefathers ofIQ testing, including Sir Francis Galton (who also pioneered the science of fingerprinting), suspected that highly intelligent people also have supersensory discrimination. But studies in the subsequent decades have found only a modest connection between IQ-test scores and peoples ability to quickly or accurately spot motion in images. Tadin and his colleagues were studying a separate question on visual perception in 12 participants when they found something striking: IQ seemed to be correlated strongly with performance on a visual task. The test asked users to spot the direction of motion on a series of black-and-white stripes on a screen. Sometimes, the lines formed inside a small central circle, and other times, they were large stripes that took up the entire screen. Participants also completed a short IQ test. [Watch Video of Motion and Test Your Smarts] The team noticed that people with higher IQs were good at spotting motion in the small circles, but terrible at detecting motion in the larger black-and-white stripes. Because they had looked at so few people, Tadin and his colleagues wondered if their results were a fluke. They repeated the experiment with 53 people, who also took a full IQ test. The ability to visually filter the motion strongly predicted IQ in fact, motion suppression (the ability to focus on the action and ignore background movements) was as predictive of total IQ as individual subsections of the IQ test itself. Relevant information As people walk, the background scenery is always changing, so efficient brains may be better at filtering out this irrelevant visual information. And that efficiency could be operating across a wide range of tasks, Tadin said. “What happens in brains of high-IQ people is, they're automatically processing motion of small moving objects efficiently, whereas they're suppressing the background,” Tadin said. The findings reshape the conventional view that quick thinking leads to smarts. “Speedy processing does matter, but it's only half the story. It's how you filter out things that are less relevant and focus your speedy resources on what is important,” Tadin said. Big variation The study reveals new insights into brain efficiency and smarts, said Kevin McGrew, director of the Institute for Applied Psychometrics and owner of www.themindhub.com. Even though the link between IQ and visual filtering was very strong, IQ tests won't be replaced by motion tracking anytime soon, said McGrew, who was not involved in the study. “Their task accounts for or explains about 50 percent of the IQ scores,” McGrew told LiveScience. “That is impressive in psychology, but it still means there is 50 percent of the scores that they're not explaining.” Copyright 2013 LiveScience, a TechMediaNetwork company. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.source : http://www.foxnews.com/health/2013/05/24/simple-vision-test-predicts-iq/

Study details genes that control whether tumors adapt or die when faced with p53 activating drugs

"The gene p53 is one of the most commonly mutated cancer genes. Tumors turn it off and then they can avoid controls that should kill them. Fine: we have drugs that can reactivate p53. But the bad news is when we go into the clinic with these drugs, only maybe one in ten tumors actually dies. …

Poliovirus vaccine trial shows early promise for recurrent glioblastoma

The treatment, developed at Duke and tested in an ongoing phase 1 study, capitalizes on the discovery that cancer cells have an abundance of receptors that work like magnets drawing the poliovirus, which then infects and kills the cells. The investigational therapy, known as PVSRIPO, uses an engineered form of the virus that is lethal to cancer cells, while harmless to normal cells. …

How gold nanoparticles can help fight ovarian cancer

The discovery is detailed in the current online issue of the Journal of Biological Chemistry. "This study identifies a novel mechanism that protects ovarian cancer cells by preventing the cell death or apoptosis which should occur when they encounter positively charged nanoparticles," say the senior authors of this study, Priyabrata Mukherjee, Ph.D., a Mayo Clinic molecular biologist, and Y. S. Prakash, M.D., Ph.D., a Mayo Clinic anesthesiologist and physiologist…

Could marijuana reduce diabetes risk?

There's an unexpected link between marijuana use and factors related to Type 2 diabetes that has medical researchers intrigued. Several studies have found that marijuana users take in more food calories than nonusers, but they still have lower rates of obesity and diabetes, and lower average body mass index (BMI) levels. In a new study, researchers investigated what effects marijuana and its active ingredient tetrahydrocannabinol (THC) might have on people's metabolism, especially insulin levels. [5 Diets That Fight Diseases] Insulin resistance an important risk factor for diabetes is a metabolic disorder that occurs when the body's cells cannot properly intake insulin. The American Heart Association estimates 35 percent of U.S. adults have metabolic disorders that include insulin resistance. To examine the link between THC and metabolism, researchers gathered the results of 4,657 adults from the National Health and Nutrition Examination Survey, a cross-sectional study administered annually by the Centers for Disease Control and Prevention. Of the study's participants, 579 were current marijuana users, 1,975 had used the drug in the past but not recently, and 2,103 had never tried marijuana. Researchers analyzed the participants' fasting insulin levels, cholesterol levels, insulin resistance and waist sizes. Multiple benefits seen The results showed that the current marijuana users had 16 percent lower fasting insulin levels than nonusers, and 17 percent lower insulin-resistance levels. Additionally, the regular users of marijuana had smaller average waist sizes, and higher levels of high-density lipoprotein (HDL) cholesterol, aka “good cholesterol.” “These are indeed remarkable observations that are supported by basic science experiments that came to similar conclusions,” Dr. Joseph Alpert, professor of medicine at the University of Arizona College of Medicine, Tucson, said in a statement. Interestingly, only the current users of marijuana (not the former users) experienced the positive results, suggesting that the effects of marijuana use on insulin and insulin resistance only occur after recent use. To test their results, which were published in the latest issue of The American Journal of Medicine, the researchers also adjusted for participants who had been diagnosed with Type 2 diabetes. Much more research needed “After we excluded those subjects with a diagnosis of diabetes the associations between marijuana use and insulin levels, [insulin resistance], waist circumference and HDL-C were similar and remained statistically significant,” Dr. Elizabeth Penner, a co-author of the study, said in a statement. “Is it possible that THC will be commonly prescribed in the future for patients with diabetes or metabolic syndrome alongside antidiabetic oral agents or insulin for improved management of this chronic illness? Only time will answer this question for us,” Alpert said in an editorial accompanying the article in the journal. “We desperately need a great deal more basic and clinical research into the short- and long-term effects of marijuana in a variety of clinical settings such as cancer, diabetes and frailty of the elderly,” Alpert wrote. Copyright 2013 LiveScience, a TechMediaNetwork company. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.source : http://www.foxnews.com/health/2013/05/16/could-marijuana-reduce-diabetes-risk/

Water governs cell movement: Aquaporins play key role, new research finds

The ability of cells to move and change shape is significant in many biological processes. White blood corpuscles gather at "hotspots" like infections and inflammations. Stem cells in the embryo move off in different directions to make the organs of the body. One unwanted movement is the movement of tumour cells, which lead to cancer metastasis…

Link between tumor suppressors and starvation survival suggested

CU-Boulder Professor Min Han said the research team was interested in how a common tumor suppressor gene known as Retinoblastoma 1, or Rb, behaved under conditions of starvation. The question is important, said Han, because it may help researchers understand why many cancer cells are more susceptible to starvation or fasting than ordinary cells. Han and his team studied a popular lab organism called C. elegans, a translucent nematode smaller than an eyelash…