Tag Archives: count

Teenagers, young adults diagnosed with cancer at increased risk of suicide

A study of nearly eight million Swedes aged 15 and over found that among the 12,669 young people diagnosed with cancer between the age of 15 and 30 there was a 60% increased risk of suicide or attempted suicide. The risk was highest during the first year immediately after diagnosis when suicidal behaviour was 1.5-fold (150%) higher among the cancer patients compared with the cancer-free group. Dr Donghao Lu, a PhD student in the Department of Medical Epidemiology and Biostatistics, Karolinska Institutet (Stockholm, Sweden), said: "We found that there were 22 suicides among the cancer patients versus 14 expected and 136 attempts at suicide versus 80 expected. This equates to an extra 64 instances of suicidal behaviour among the 12,669 young cancer people…

Mutations in novel tumor suppressor gene associated with early onset breast cancer

The rare mutations in RINT1, a tumor suppressor gene, were detected in three of 49 families participating in a study that sequenced the whole exome, the protein-coding DNA, of families with multiple individuals affected by breast cancer. …

Estimate of amount of radiotherapy dose wasted in compensating for tumour growth between treatments

In research to be presented to the 2013 European Cancer Congress (ECC2013), Professor John Yarnold will say that, until now, there has been contradictory evidence as to whether gaps between radiotherapy treatments, for instance overnight or at weekends, makes any difference to the overall effectiveness of radiotherapy on breast cancer, and, if it does make a difference, why that could be. "Traditionally, breast cancer has not been regarded as a fast growing cancer, unlike some other cancer types, but our research now suggests that a significant part of the daily radiotherapy curative dose is ‘used up’ in compensating for tumour growth overnight and over weekends. We have estimated that the amount of radiotherapy dose that is used up in this way corresponds to approximately 0.60 Gray (Gy) per day," says Prof Yarnold, who is Professor of Clinical Oncology at The Institute of Cancer Research, London, and Honorary Consultant at the Royal Marsden NHS Foundation Trust (London, UK). "This is the first numerical estimate to suggest that the duration of a course of radiotherapy has an effect on local cancer cure for patients with early breast cancer…

Proteins identified that may help brain tumors spread

Gliomas account for about a third of brain tumors, and survival rates are poor; only about half of the 10,000 Americans diagnosed with malignant glioma survive the first year, and only about one quarter survive for two years. “Malignant gliomas are notorious, not only because of their resistance to conventional chemotherapy and radiation therapy, but also for their ability to invade the surrounding brain, thus causing neurological impairment and death,” said Hassan Fathallah-Shaykh, M.D., Ph.D., associate professor in the UAB Department of Neurology. “Brain invasion, a hallmark of gliomas, also helps glioma cells evade therapeutic strategies.” Fathallah-Shaykh said there is a great deal of interest among scientists in the idea that a low-oxygen environment induces glioma cells to react with aggressive movement, migration and brain invasion…

New mutation identified, associated with better survival in lung cancer patients

Lung cancer is the leading cause of cancer-related deaths in many industrialized countries. Most deaths are due to long-term exposure to cigarette smoke, but non-smokers account for 10 — 15% of cases. …

Clinical tool classifies spots on lung scans of smokers

The findings are expected to have immediate clinical impact worldwide among health professionals who currently diagnose and treat individuals at risk for or who are diagnosed with lung cancer, and provide new evidence for developing and improving lung-cancer screening programs. A total of 12,029 lung cancer nodules observed on CTs of 2,961 current and former smokers were examined in the population-based study. The results, to be published in the Sept. 5th issue of the New England Journal of Medicine (NEJM), will have an immediate impact on clinical practice, says co-principal investigator Dr. …

Strong pregnancy outcomes for survivors of childhood cancer

"Most women think that if they had cancer as a child, then they’ll never have children. It turns out that many of them can get pregnant. It just might be a little harder," said senior author Lisa Diller, MD, chief medical officer of Dana-Farber/Boston Children’s and medical director of the David B…