The results provide some of the most dramatic evidence to date of the potential of therapies that increase the ability of the immune system to kill cancer cells. While clinical trials of such immunotherapies in other cancers have shown them to be highly effective in a subgroup of patients, the new study stands out because nearly all patients benefited from the treatment…
The question becomes who is invading whom — do cancer cells invade the basement membrane or do some fibroblasts help invading cancers? Researchers at the Institut Curie in Paris now say that they have evidence of a coordinated attack on the basement membrane by cancer cells in situ and CAF cells in the extracellular matrix that begins long before the actual translocation of cancer cells. …
The new report by Cancer Research UK and the National Cancer Intelligence Network reveals the difference in rates of surgery across 21 different cancer types. While many factors might be at play — frailty, suffering more than one illness, being diagnosed at a late stage, patients choosing not to undergo surgery — these statistics paint a worrying picture. Younger cancer patients were more likely to have surgery for 19 cancer types, with the largest differences between age groups seen in kidney and ovarian cancers. …
Published online Dec. …
The current study results revolve around proteinases, enzymes that break down proteins as part of cellular life. Matrix metalloproteinases or MMPs specifically target the extracellular matrix, the non-cell, structural framework within tissues. Beyond that role, the new study found that one member of this family, MMP-2, has another signaling role related to the human immune system. It may shift a set of cells to become part of immune response that accelerates healing in some cases, but may worsen inflammatory disease in others. …
“A comprehensive geriatric assessment of elderly patients who are being evaluated for the Whipple procedure is essential,” said lead study author Dominic Sanford, MD, MPHS, a general surgery resident at the Washington University School of Medicine, St. …
The results of their study appear online in the journal Nature today. “Treatment for advanced bladder cancer is limited to surgery and chemotherapy…
Traditionally used to detect cancer, PET imaging shows how organs and tissues are functioning. When used with X-rays generated from CT scans, PET scans provide a more complete picture of the area of the body being examined…
The numbers add up to a strong economic case to invest in services to support mums to carry on breastfeeding, they conclude. In common with many other high income countries, breastfeeding rates in the UK are low, and to find out if boosting these could cut healthcare costs by improving mother and child health, the researchers focused on five priority diseases…
Bladder cancer is the ninth most common cancer in the world, with 430,000 new cases diagnosed in 2012. Europe and North America have the highest incidence of bladder cancer, with an even higher incidence in people with diabetes…