Tag Archives: ccc

Tumor determination in bowel cancer: Blood test replaces surgery

One of the challenges of personalised medicine is the development of treatment resistance. At the Comprehensive Cancer Center (CCC) Vienna at the MedUni Vienna and Vienna General Hospital, a study is now commencing which involves patients with metastasized bowel cancer who are undergoing a new diagnostic method, namely liquid biopsy in the form of a blood test. The aim of this new method is to spot a tumor’s development of resistance early on and therefore adjust the treatment quickly and in a targeted manner…

Metastatic brain tumor treatment could be on the horizon with use of SapC-DOPS — ScienceDaily

However, a new Cincinnati Cancer Center (CCC) study, published in the advance online edition of the journal Oncotarget, provides hope that previously studied SapC-DOPS could be used for treatment of brain cancer that has spread. Xiaoyang Qi, PhD, member of the CCC, associate director and associate professor in the division of hematology oncology at the University of Cincinnati (UC) College of Medicine and a member of the UC Cancer and Neuroscience Institutes and the Brain Tumor Center, says this critical data shows promise for finding treatment for one of the deadliest cancers. A lysosomal protein saposin C (SapC), and a phospholipid, known as dioleoylphosphatidylserine (DOPS), can be combined and assembled into tiny cavities, or nanovesicles, to target and kill many forms of cancer cells…

Regulation of cancer-causing protein could lead to new therapeutic targets

Atsuo Sasaki, PhD, a member of the CCC, the UC Cancer Institute and the UC Brain Tumor Center as well as an assistant professor in the division of hematology oncology within the department of internal medicine, is the principal investigator on the study, which is published in the Dec. 13, 2013, online edition of the Journal of Biological Chemistry. …