Tag Archives: cardiovascular

Women prescribed hormone therapy should use caution when taking apigenin supplement

A new study shows that when the supplement apigenin is ingested in a diet at the same concentration as subjects received during IV injections in previous studies — the benefits were reversed leading to a higher incidence of cancerous tumors in subjects receiving progestin. "Typically, hormone replacement therapies improve the lives of menopausal women and achieve very good results," said Salman Hyder, the Zalk Endowed Professor in Tumor Angiogenesis and professor of biomedical sciences in the College of Veterinary Medicine and the Dalton Cardiovascular Research Center. "However, research has proven that in women receiving therapies that involve a combination of the natural component estrogen and the synthetic progestin, a higher incidence of breast cancer tumors can occur." Hyder explains that many women normally have benign lesions in breast tissue. These lesions don’t typically form tumors until they receive the "trigger" that attracts blood vessels to cells essentially feeding the lesions causing them to form and expand — in this case, progestin is the trigger…

MRI detects early effects of chemotherapy on children’s hearts

Chemotherapy with anthracyclines, such as Doxorubicin, is one of the most effective treatments against many types of cancer, including leukaemia and Hodgkin’s lymphoma, breast, lung, and ovarian cancer. However it can also lead to irreversible heart damage, which may not be apparent until several years after treatment. Being able to detect this damage at an early stage, in order to initiate preventative therapy of affected people, is especially important in children. Researchers from University of Alberta performed MRI scans on children and young adults (aged 7 to 19) at the Stollery Children’s Hospital who were in remission following anthracycline treatment…