Esophageal cancer chemotherapy drug oxaliplatin reviews Comments oxaliplatin, oxaliplatin is the 3rd generation of lead drugs, preclinical and Phase I, E clinical study confirmed that prominent effect on colorectal cancer, ovarian cancer and non-Hodgkin's lymphoma good effect, blood toxicity was mild , no renal toxicity, high incidence of peripheral nerve toxicity, but is reversible, and… Read More »
Esophageal cancer chemotherapy drug mitoxantrone aminoguanidine hydrazone Study C squint tracking the Freedlander and French in 1958 were synthesized and used in animal experiments, found that mice with L1210 leukemia on the anti-tumor effect. Experimental Study of mitoxantrone guanidine hydrazone, 1961 Regelson and Holland began clinical trials; the same year, Freireich, etc. I started on… Read More »
Methotrexate ra folic acid category for the anticancer agent is a cell cycle specific drugs.Methotrexate ra experimental study in 1949 by the Seager synthesis, for the treatment of leukemia in 1953, and achieved a certain effect. MTX and folic acid chemical structure similar to a major role in cell cycle S phase, in vivo competitive… Read More »
Experimental Study of Etoposide soft capsules, oral etoposide capsules mechanism of VP-16 and VP-16 used the same vein, the role of topoisomerase sites are IT, development of drug among a stable enzyme-DNA can be split complexes, DNA damage and interference re-repair. It was found that compounds with VP-16 can be reversed by the elimination, so… Read More »
IFO is a nitrogen mustard agent and the cell cycle class of melted non-specific drugs, as the isomers of cyclophosphamide.Experimental study of ifosfamide, first synthesized by German pharmaceutical company Asta on transplanted tumor in mice Lewis lung cancer and sarcoma 180 tumor growth and the role of different levels, and a dose-effect relationship. Experimental study… Read More »
Experimental study of mitomycin C, the drug is cell cycle non-specific drugs, in 1955 by Japanese scholar Qin rattan trees isolated in Tokyo, two kinds of soil actinomycetes Strepto-myees caespitosus, found that the medium can inhibit tumor effect. 1958, if the wood has improved extraction method and found a with A, B different purple crystals,… Read More »
In 1963, the short leaf from the Pacific Northwest yew bark is found on many tumor cytotoxicity of natural substances. 1971, the active ingredients extracted paclitaxel, screening with anti-tumor effect. U.S. National Cancer Institute in 1979, thousands of plant species on natural anti-tumor activity of extracts were screened and found that Taxol is one of… Read More »
U.S. researchers have said before, due to BRCA1 and BRCA2 gene mutations in women with high risk of cancer in the ovaries and fallopian tubes to do surgery, the risk of ovarian cancer and fallopian tube cancer risk will be reduced by 80%, but they may still be suffering from breast cancer, that ovarian surgery… Read More »
A long time, people thought that only adults or older personnel suffering from cancer, is not the case, along with the serious pollution of life, many children also become susceptible tumors. And "difficult to find, easy to delay" is the most horrible place children's cancer. Because clinical symptoms and some common diseases are very similar,… Read More »
Uterine fibroids prior disease, generally thought to be due directly to the basal layer of the endometrium caused by the growth of myometrial invasion. Under normal circumstances, there is some kind of defense myometrium, can resist the invasion of the endometrium. If due to multiple pregnancy, childbirth, or curettage uterine wall causing damage, or due… Read More »