Preoperative chemotherapy of gastrointestinal tumors

By | October 18, 2011

Gastrointestinal tract is one of the most common malignant tumor, among which the stomach and large intestine are more common. In recent years, the latest progress of their treatment is as follows:
Preoperative chemotherapy of gastrointestinal tumors in the gastrointestinal tract in the treatment of attention. Preoperative chemotherapy to reduce the cancer cells with energy, making the tumor shrink, reducing intraoperative iatrogenic spread and liver metastasis and improve the curative resection rate and so on. Preoperative chemotherapy for gastrointestinal therapeutic intervention for the induction of the major mechanisms of apoptosis, inhibit cancer cell proliferation and tumor pathological necrosis.
Preoperative chemotherapy for gastrointestinal pathology observed total effective rate was 60% – 75%. There studies have shown that preoperative chemotherapy can significantly reduce the intervention of colorectal tumor microvessel density, so that patients bleeding, diarrhea, and intestinal obstruction symptoms significantly improved. But the preoperative chemotherapy of gastrointestinal cancer patients with malignant tumors of the gastrointestinal tract of surgical outcomes have yet to be clinically exact bulk cases, multi-center randomized controlled study and strict to be further explored.

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