Origin of malignant lymphoma is a malignant tumor lymphatic network system. International will be divided into Hodgkin's lymphoma patients (lID) and non-Hodgkin lymphoma (NHL) two broad categories.
Malignant lymphoma in our country have the following characteristics:
morbidity and mortality in coastal and central than the Mainland.
the peak age of onset curve is about 40 years old, was a single peak.
In the non-Hodgkin's lymphoma is very low proportion of follicular, diffuse majority.
Signs of malignant lymphoma
1. Lymph nodes
Lymph nodes as the main signs of malignant lymphoma. Superficial lymph nodes of painless, progressive enlargement is often the first manifestation, particularly in the neck lymph nodes is more common, followed by the arm. Supraclavicular lymph nodes prompted lesions have spread, right from the mediastinum or lungs, usually from the left retroperitoneal. Hodgkin's disease first appeared in cervical lymph nodes accounted for 60% to 70%, left more than right.
2. Signs of extranodal disease
(1) non-Hodgkin's lymphoma in the chest, about 25% of pleural effusion in the course of the disease, in addition to foreign invasion of mediastinal involvement may also, due to lymphatic obstruction.
(2) invasion of liver parenchyma can cause liver and spleen enlargement, spleen and abdominal lymph node infiltration of lesions by mostly by lymphatic spread from.
(3) diversification of skin manifestations, including tumors, ulcers, subcutaneous nodules, infiltrative plaques, rash, rash hills, etc, often first seen in head and neck.
(4), malignant lymphoma of bone can have partial skeleton by tenderness, pathologic fracture.
(5), tonsils and mouth, nose, throat lymphoma mouth, nose, throat who, location up to the soft palate, tonsils, followed by nasal cavity and paranasal sinuses, nasopharynx and base of the tongue less. Clinical signs of focally malignant tumor and the submandibular lymph nodes.
(6) involving the central nervous system nervous system symptoms caused by an appointment in 10% of the non-Hodgkin's lymphoma, particularly diffuse the original cells, small non-cleaved and large cell lymphoma.
(7), renal enlargement, high blood pressure and blood urea nitrogen retention, others still see pyelonephritis, hydronephrosis, renal infarction, amyloidosis, and so on.