Pathology of colorectal cancer

By | May 4, 2012

Pathology of colorectal cancer, colorectal cancer in the colon to the rectum of each section of the distribution of most progressive reduction of the paragraph by paragraph, to the cecum and increased. In colorectal cancer-prone areas, simultaneously or successively appear multiple colorectal more. Medical Cancer Hospital data show that multiple colorectal cancer accounts for about 2%. Therefore be thoroughly checked before treatment of colorectal paragraphs, to avoid missing lesions; closely followed up after treatment, should be followed up carefully check the remaining part of the large intestine.
Colorectal cancer is the formation of the basic pathological lumps, ulcers, and invasion, pathological specimens often exist for each of these three changes, but often in some form of change-based. Naked eye (in general) see colorectal cancer can be divided into three types:
1. Protruded cauliflower-like tumor or nodular growth of the cavity, the surface is not smooth, often shallow ulcers of different sizes. Tumor at the base wider involvement of local wall thickening. Later occurred to the deep tissue invasion and metastasis, the prognosis is good. This type occurred in the right colon.
2. Invasive growth of tumor infiltration mainly along the intestinal snapped, so that bowel wall thickening; gradually involving the bowel for the week, so that the narrow lumen into thin tube, prone to intestinal obstruction. Mucosal surface more than the flat, smooth or slightly thickened, slightly granular. Poorly differentiated cancer cells, lymphatic and blood transfer earlier. This type occurred in the left colon.
3. Ulcerated The most common type, accounting for more than half of colon cancer. Tumor growth, such as a flat dish, a few broke into the intestine, after its central ulceration rapidly, forming large irregular ulcers; ulcer edge of the uplift, the rugged, like the fall volcanic crater. As infiltration significantly, can affect the intestinal wall for the week, the prognosis is poor. Ulcers penetrate the intestinal wall, and nearby organs sinus adhesion formation. This type of cancer, poorly differentiated, often early lymph node metastasis.
Colorectal pathology, histology, the majority of colorectal cancer are adenocarcinoma, squamous cell carcinoma and small glands are squamous cell carcinoma. Adenocarcinoma cells much less fibrous tissue called medullary carcinoma who or soft cancer; the other hand, less cancer, who said more hard fibrous tissue cancer. Mucus secreted by cancer cells, said a large number of mucinous adenocarcinoma, it is also known for its cut surface plastic jelly-like carcinoma.

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