Mucoepidermoid carcinoma of the lung pathological features

By | March 27, 2012

Mucoepidermoid carcinoma of the lung pathological features:
Mucoepidermoid carcinoma of the lung pathology characteristic 1) In general: general than the L-MEC tumors larger boundaries of the tumor and surrounding lung tissue is unclear, necrosis common.
Mucoepidermoid carcinoma of the lung pathology characteristic 2) microscope: the main components and structure of L-MEC roughly the same. But the tumor tissues, cells significantly increased, while the squamous component and the relatively small number of glands. Cells obviously, especially the pleomorphic tumor cell nuclei: size, shape varies; nuclear stained, obviously, more common nuclear fission, the average mitotic index of 4 OHPF. In addition, tissue necrosis can; invasive growth, invasion and strong, common lymph node metastasis.
Mucoepidermoid carcinoma should pay attention: This tumor occurs in the central hilar region; tumor-order-like cells, intermediate cells and have taught fluid cells; three types of cells in the tumor tissue of the opposite sex Repentance mixed performance for the squamous cell nests Central emergence of differentiation and maturation of small focal adhesion air cells.
MEC and liquid staining: positive for glandular secretions, including station fluid cells were nested. Carcinoma of the CEA, EMA and cytokeratin were generally positive. 5-100 protein derived markers negative or a few cells weakly positive.
Mucoepidermoid carcinoma of the lung pathological features (3) prognosis: MEC's prognosis is usually better than adenoid cystic carcinoma. Better than high after low malignant evil. After tumor resection in pediatric patients, particularly ideal.

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