Mucoepidermoid carcinoma of the lung pathology and clinical diagnosis

By | March 27, 2012

Mucoepidermoid carcinoma based on tumor cells and clinical point of chess is divided into two types, namely low grade and high grade.
Mucoepidermoid carcinoma of the lung pathology and clinical diagnosis of 1) low-grade mucoepidermoid carcinoma
general features: The tumor was polypoid, exogenous growth, the sudden to the bronchial lumen, adjusting focal overlying mucosa was ulcer or squamous metaplasia. Swollen hard material; section gray. Report Run bronchial tumor and spread along the bronchial branches, puncture the bronchial wall, infiltrating the surrounding lung parenchyma to form lumps. Boundaries of the tumor and surrounding lung tissue more clearly, but no capsule. Are small cysts or masses can be obvious cystic change. Minimal tumor necrosis. Tumor associated with obstructive pneumonia distal bronchiectasis.
microscope: Mucoepidermoid carcinoma of the lung pathology and clinical diagnosis, tumor tissue from the squamous cells, mucus secreting cells and intermediate cells, we can see the nest and eosinophils of clear cell nests. Tumor cells in solid nests or tubular. Squamous cells and (or) intermediate cell and teaching specific solution was mixed secretory cells.
Mucoepidermoid carcinoma of the lung pathology and clinical diagnosis, the typical structure can be seen:
a. duct area: squamous cell nests, and (or) nest in the middle of the number of cells ranging from cell nests produce dynamic fluid, the mucus cells form acinar or duct-like structure. Dilated cystic duct.
b. the solid areas: the squamous cells, intermediate cells, clear cells and eosinophils island shape. Eosinophilic cytoplasm of squamous cells, showing intercellular bridges; keratosis keratosis beads and cells is not obvious. Squamous cells and intermediate cells with mild pleomorphism; a small number of nuclear fission, 20 no more than 1 high power field; no necrosis; matrix transparent change, may have mild chronic inflammatory cells, calcification and ossification may occur.

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