WDFA disease in all age can be, and no gender differences. Most patients with clinical symptoms of ignorance, but a few may present with respiratory tract infection symptoms such as fever, cough, chest discomfort.
Well-differentiated fetal adenocarcinoma of the description 1) general pathological features: well-differentiated fetal adenocarcinoma, more common in the peripheral lung. General examination can be found: tumor without capsule, cut gray, necrosis is not obvious, a clear demarcation between tumor and surrounding tissue.
Well-differentiated fetal adenocarcinoma of the description 2) microscopic features: tubular or adenoid structures composed of cancer cells, there is no envelope, but a clear demarcation with the surrounding tissue. 1-2 layer or multilayer coating glandular epithelial cells; cell morphology more like, rich in glycogen, no cilia, similar to fetal lung tubules; tumor cells Nucleation nucleus glycogen vacuole, similar to endometrial cancer. With the diagnosis that the tumor cells in solid mass, and even broke into the lumen of the body shape of Sang, the tumor cells polygonal, eosinophilic cytoplasm particles, but some may also be Sang very transparent body cells. Tubular structure of the nucleus small, deeply stained, mild atypia, nucleoli not obvious; Sang nucleus even more people. Vacuoles, showing that small nucleoli, mitotic figures visible. Carcinoma shows small focal necrosis. Benign fibrous connective tissue with lymphocytic infiltration. A small number of well-differentiated fetal gonads, tissue sections of cases, can be mixed with other common lung cancer subtype.
Well-differentiated fetal adenocarcinoma of the description 3) well-differentiated fetal adenocarcinoma of the diagnostic points: differentiated endometrial cancer samples similar to cancer, the nuclear and (or) Nucleation glycogen vacuoles; epithelial cells from the solid nests Sang very body composition; cell nuclear atypia was not obvious; a small amount of necrosis and nuclear differentiation.
Well-differentiated fetal adenocarcinoma of the description 4) differential diagnosis
lung cancer and lung glandular cancer glandular echinoderms: lung cancer and lung glandular cancer glandular echinoderms and similar well-differentiated fetal adenocarcinoma, adenocarcinoma in addition to cancer, but still shows solid epithelial cell nests. Identification of the attention; a. well-differentiated fetal adenocarcinoma of the solid epithelial cell nests are penetrated! Gland cavity, solid epithelial cell nests of cells, the lack of hierarchical structure, no intercellular bridges, and keratosis, or angle but not cell the formation of beads; lung cancer and lung glandular cancer glandular echinoderms, solid epithelial cell nests were layered structure can be seen the bridge between cells and (or) cell keratinization, keratin pearls formation; b. well-differentiated fetal adenocarcinoma, was well differentiated adenocarcinoma, tubular structures and cell atypia was not obvious; and adenosquamous carcinoma of the lung and lung echinoderms gland carcinoma, adenocarcinoma, clear atypia, necrosis, and nuclear fission is easy to see.
biphasic pulmonary blastoma: biphasic pulmonary blastoma with well-differentiated fetal adenocarcinoma, have differentiated adenocarcinoma, well differentiated fetal adenocarcinoma of the stroma is benign, the mother of two-phase pulmonary stromal cell tumors are sarcomas, can be a fibrosarcoma, rhabdomyosarcoma, bone or cartilage sarcoma, malignant fibrous histiocytoma.
Introduced well-differentiated fetal adenocarcinoma 5) prognosis: well-differentiated fetal adenocarcinoma, the prognosis is more common in female lung cancer subtypes and tumor cells called the fine as well. Common subtype of lung cancer on average 5-year survival rate was 42%, far lower than the well-differentiated fetal adenocarcinoma of the lung 86%.
- fetal adenocarcinoma stage 4 poorly differentiated