Note paclitaxel (1) treatment should be preceded by the adrenal cortex hormones (such as DXM), diphenhydramine and Hz receptor antagonists (such as cimetidine or ranitidine) treatment.
(2) should not dilute the concentrated liquid contact with PVC (PVC) equipment or equipment, and can not be used for intravenous drugs. Diluted solution should be stored in bottles (glass, polypropylene) or plastic bags (polypropylene, polyolefin short class), using polyethylene intravenous drug delivery devices.
Note paclitaxel (3) whether the administration should pay attention during the allergy symptoms and changes in vital signs. Each dose should be started within 1h 15min blood pressure, heart rate and breathing a time, to observe whether the allergic reaction.
(4) preparation of the drug required to wear gloves. Such as skin contact with the drug, immediately wash thoroughly with soap and water; eyes or mucous membrane exposure to the drug, rinse thoroughly with water.
Paclitaxel precautions (5) injection of the drug concentration must be diluted to a concentration of O.3–1.2mg/ml solution can be used. Free saline, dextrose 5% glucose injection or diluted in normal saline.
(6) preparation of a good solution of the drug at room temperature (15 – 25 C) is stable cents, it is recommended to use immediately after preparation.
Note paclitaxel (7) intravenously once a liquid leakage when the blood vessels outside the immediate cessation of administration, local cold, and with 1% procaine partially closed.