Early signs of leukemia include the following:
Early signs of leukemia (1) anemia
Symptoms of anemia in patients with acute leukemia often appear too early and severe, often led from the performance, about 2 / 3 of patients with moderate anemia in some of the time of diagnosis before the onset of acute leukemia a few months or even years, there may be refractory anemia. The main reason for the anemia of leukemia cell proliferation to normal erythroid progenitor cell production was inhibited; followed by ineffective erythropoiesis, hemolysis and blood loss after the hemorrhage; but the main reason is to reduce red blood cells. Chronic leukemia usually occurs late in the disease anemia.
Early signs of leukemia (2) fever
Fever is also common symptoms of acute leukemia, one of about half of patients with fever onset. When the body temperature> 38.5 C is often caused by infection. Infection with angina, stomatitis, pulmonary infection, inflammation, and Hong Zhou Hong Zhou most common version of swelling. In addition to the infection outside the leukemia itself can cause fever, heat the tumor, but the proportion of very little. CLL patients are also prone to infections, particularly pneumonia, may be due to reduction or gamma globulin due to neutropenia.
Early signs of leukemia (3) bleeding
Acute leukemia is the main performance. 840 cases of leukemia in Shanghai, according to analysis to bleeding accounted for the early manifestation of adult acute leukemia 38.6%. Bleeding sites are widely distributed to the most common skin and mucous membrane bleeding, menorrhagia menstrual women often accompanied by severe internal bleeding that can be expressed as, or even intracranial hemorrhage. Bleeding was mainly due to thrombocytopenia, but also involves the vessel wall, coagulation factors, fibrinolysis system and platelet quality problems may also be secondary to disseminated intravascular coagulation. This is common in acute promyelocytic leukemia.
(4) lymph nodes
In patients with CLL and acute lymphoblastic the most common. 70% and 50% of CLL diagnosed with acute lymphoblastic lymphadenopathy. Mostly systemic, common in the neck, armpits, groin, etc., mild to moderate enlargement of lymph nodes, texture, medium hardness, no tenderness and adhesion, increases with the progression of the disease, visceral lymph nodes may compress the dirt around symptoms resulting from a corresponding device. In the acute Feilin in acute myelomonocytic and acute to a single lymph node enlargement common, but more acute lymphoblastic acute Feilin common.
Mostly mild to moderate hepatomegaly. Of acute lymphoblastic leukemia in the liver, the most significant splenomegaly. CML splenomegaly is an important sign, about 90% of the patients had splenomegaly, mild to severe swelling, splenomegaly can be inserted into the pelvic cavity, hard and no tenderness, swelling of the spleen, often causing left abdominal discomfort, full sense of swelling and stretching. Some patients with splenomegaly was found in the physical examination, and further examination confirmed with CML.
Early signs of leukemia (6) abnormal blood
When suspected of having leukemia, the first need for the blood test. Most of increase in white blood cells of leukemia patients, is generally (l0-100) x109, Zhuang, classification can be seen in peripheral blood blast cells for bone marrow puncture point needs further examination to confirm the diagnosis. A small number of patients with low white blood cell counts in peripheral blood smear is no naive cells, this type of leukemia known as "non-leukemia leukemia."
- late onset leukemia