Adenocarcinoma subtype of lung cancer often presents as a mixture of the organization

By | March 30, 2012

Adenocarcinoma subtype of lung cancer often has mixed organization like. The most common mix is: alveolar type and papillary type; solid type with bronchioloalveolar type. When the adenocarcinoma tumor diameter <2cm, the adenocarcinoma often by a single type of cells, the formation of a single histological type.
Adenocarcinoma subtype of lung cancer often presents as a mixture of organization (1) acinar adenocarcinoma (acinar type): adenocarcinoma tissue from the acinar and duct (tubular) form. Interstitial infiltration of cancer tissue, blood vessels and pleura. Columnar or cuboidal cells, the cytoplasm and glandular lumen visible mucus. Acinar adenocarcinoma of the lung cancer the most common, accounting for 80% of lung cancer. According to cell differentiation and tissue structure, can be divided into well-differentiated acinar carcinoma, moderately differentiated and poorly differentiated acinar carcinoma acinar carcinoma.
Adenocarcinoma subtype of lung cancer often presents as a mixture of the organization (2) papillary adenocarcinoma (papillary adenocarcinoma): papillary adenocarcinoma and adenocarcinoma of the structure accounts for more than 75%, then known as papillary adenocarcinoma. Papillary carcinoma is more common in lung cancer histological type, accounting for about 20% of lung cancer.
Papillary carcinoma can be divided into two types: from the cubic to the low columnar cells, with 2 ~ 3 complex branches of the nipple, cancer cells do not produce mucus; by high columnar or cuboidal cells that nipple, cancer cells does not produce mucus or mucus, accompanied by fibrovascular stroma, carcinoma invasion lung parenchyma.
Adenocarcinoma subtype of lung cancer often presents as a mixture of tissue (3) bronchioloalveolar carcinoma (hronchioloalveolar carcinoma, BAC): along the airway of lung cancer proliferation, cancer cells showed a paving-like or scaly (lepidic) growth, not associated with interstitial, vascular and pleural invasion.


  • multifocal mederate differentiated lung carcinoma acinar-predominant 80% and papillary 20%

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