Chemotherapy of breast cancer – Neoadjuvant chemotherapy

By | April 6, 2012

Chemotherapy of breast cancer – neoadjuvant chemotherapy, neoadjuvant chemotherapy (Neoadjuvant chemotherapy) with breast cancer adjuvant chemotherapy relative named, refers to the local surgery or radiotherapy before treatment with systemic chemotherapy for breast The first step in cancer treatment, then topical treatment.
(A) Indications
1. The primary tumor is big, can sub-surgery breast cancer breast surgery to be secured.
2. Locally advanced invasive breast cancer preoperative chemotherapy.
3. May be in the surgery of breast cancer neoadjuvant chemotherapy.
(B) to breast conserving surgery preoperative neoadjuvant chemotherapy
1. Prior chemotherapy
(1) to retain the breast of patients, neoadjuvant chemotherapy before the tumor core needle biopsy should be performed to confirm the diagnosis.
(2) MRI examination to understand the scope of the breast lesion and axillary lymph node status.
(3) neoadjuvant chemotherapy before surgery will still need to locate the tumor bed and were estrogen and progesterone receptor determination, recommended for all newly diagnosed patients with invasive breast cancer HER-2/neu expression levels were determined.
(4), bone alkaline phosphatase increased locally or T3N1MO symptoms or patients with bone scan line. IIA or IIB period, elevated alkaline phosphatase or liver dysfunction T3N1MO patients undergoing abdominal CT or MRI or ultrasound.
(5) clinical axillary lymph node-positive, a lymph node fine needle aspiration cytology.
Breast cancer chemotherapy – chemotherapy, 2. Neoadjuvant treatment choice is generally believed that effective adjuvant chemotherapy in the neoadjuvant chemotherapy program can be used, the principle of selection should still be considered disease stage, receptor status and HER-2/neu levels and other factors.
(1) HER-2/neu negative patients, the proposed program-based neoadjuvant FAC chemotherapy. If possible, can also choose other options, there are NP, FEC, AC and so on.
[1] [2] Next

Leave a Reply

Your email address will not be published. Required fields are marked *