Pathomorphology of esophageal cancer type of paragraph 1. Early esophageal cancer pathology
Early esophageal cancer lesion only involved the epithelium, lamina propria into the submucosa, without invasion, and muscle, without lymph node metastasis can be divided into four types.
(1) HIDDEN: Fresh specimens of lesions seen on mucous membranes except the color slightly darker than normal, the visual inspection difficult to detect, can be seen fixed specimens of esophageal mucosal surface subsidence and a slight wrinkle Fan disorder, only in the microscopic examination can determine the time lesions with the site, microscope as carcinoma in situ, is the most early stage esophageal cancer.
(2) erosive: Hong rotten little mucous membrane lesions or subsidence, shape and sizes, the edge of the map was kind of irregular, clear boundaries with the surrounding mucosa. Erosion at the mucosal fold bags break, darker color, showing fine granular, occasional remnants of the normal island. Carcinoma in situ or with an early invasion. Surgical resection of early esophageal cancer in the more common.
(3) plaque-type: bulge slightly swollen mucous membrane lesions, showing thick granular, gray, leather-like addiction, clear boundary, the maximum plaque diameter less than 2cm, section dense texture, the thickness of 3mm or more larger in scope plaque-type cases, multiple small superficial sometimes seen What rotten or horizontal War. Normal esophageal mucosa ruffling gloss and structure interrupted. Pathology of early invasive carcinoma is a tumor invasion and muscularis mucosa and submucosa.
(4) nipple type: the tumor smaller and showed a nodular, papillary or free-shaped uplift, the edge of the clear boundaries with the surrounding mucosa, base of the pedunculated, tumor diameter 1_3cm, the surface can be covered with exudation. In the section, the tumor cavity to the esophagus prominent, visible fine arrangement of stripes, infiltration of clear, microscopic examination showed a papillary carcinoma see the growth, differentiation is better, this type is less common in early esophageal cancer.
Lesion length of each type of esophageal cancer and esophageal circumference range of violations of different types in the lcm hidden within the plaque and the cheap half of the bad type is more than 2cm. Violations of plaque-type and erosive esophagitis all or most of circumference.
Pathomorphology of esophageal cancer type of paragraph 2. In the pathological type of advanced esophageal deer
Pathomorphology of esophageal cancer type of segment, in advanced esophageal lesions involving the epithelium and lamina propria or submucosa, muscle, lymph node metastasis. Can be divided into the following five types:
(1) medullary type: tumor invading the esophageal wall layers, and around the lumen and external to the cavity expansion was swollen thickness of esophageal wall invasion, tumor surface often shades of ulcer, the majority of cancer involving the esophagus all or most of the perimeter, approximately half of the cases of more than Serna gray cut surface, hard, muscular layer of the esophagus has been through the surrounding connective tissue.
(2) Grass umbrella: carcinoid tumor is oval, flattened mass, the esophageal lumen was mushroom-like protrusions, the surface more than a superficial stains War, the bottom of the rugged, accounting for the majority of esophageal tumor or a large part of the perimeter section. Section, the tumor growth of the main cavity to the esophagus. May be infiltrating the deep esophageal wall.
(3), ulcerative: Esophageal cancer has infiltrated the surrounding fibrous tissue, tumor deep ulcer formed on the surface, reading War smoother edges, slightly down from a few. Ulcer bottom of the rugged, ulcer surface inflammatory exudate. Thin section view of the tumor, ulcer bottom of the tumor less.
(4) narrowing the type: violation of esophageal tumor the week to form a distinct ring stenosis or obstruction, tumor size is about 3cm in general, rarely more than 5cm, unclear boundaries of the tumor and surrounding tissue, esophageal mucosa showed concentric contraction, significant expansion of the proximal esophagus, esophageal cancer and more violations of muscle, and sometimes through the whole layer of the esophagus. Section structure is dense, rich proliferation of connective tissue.
(5) cavity-type: The tumor was pedunculated polyp-like protrusion to the esophageal lumen, were round or oval, often with a wide food base wall connected to irregular tumor surface erosion or a small ulcer, cancer can be myometrial invasion, depth of invasion are generally higher than the previous type of light.