The clinical impact of prognostic factors for liver cancer after many, through the review of clinical data and research, currently considered the following factors affecting the prognostic factors for liver cancer patients is more precise:
(1) the number of metastases: Wagner reported that the transfer of single leaf solitary metastatic liver cancer resection patients, the median survival was 21 months, and many stoves are only 15 months. Goslin reported 3 or fewer liver metastases after resection of liver metastases in patients median survival was 24 months, and four or more only 10 months.
(2) after resection of primary tumor diagnosis and liver disease-free interval between: Haghes retrospective studies have shown that disease-free survival after surgery for more than 12 months between the cases of liver cancer, liver metastases 5-year survival after resection 42%, no disease-free survival of less than 12 months between the 5-year survival rate of only 2%.
(3) adequate tumor-free surgical margin: the so-called tumor-free margin is the removal of liver metastases during surgery need to be removed when the part of the normal liver, to ensure that no residual tumor margin to ensure that radical surgery. Cady reported no larger than 1 cm tumor margin resection of liver cancer patients after 5-year survival rate was 60%, negative margins and no less than 1 cm tumor margin 5-year survival rate was 30%, while the positive margin 5-year survivors of those dollars.
In addition, the impact of prognostic factors for postoperative liver metastases. There extrahepatic recurrence, extrahepatic metastases (even if it can resection), tumor differentiation is low, when the primary tumor resection with lymph node metastasis had a poor prognosis.