Clinical and pathological classification of esophageal adenocarcinoma

By | March 24, 2012

Esophageal adenocarcinoma, including adenocarcinoma, simple, glandular esophageal squamous cell carcinoma, adenoid cystic carcinoma, mucoepidermoid carcinoma, accounting for 1% -7%, the other two categories are extremely rare. Adenocarcinoma of the esophagus are as follows now.
Clinicopathological classification of esophageal adenocarcinoma (1) Simple adenocarcinoma. Which is usually the most common cancer, showed a cubic or columnar cells, nuclear were round, oval or like-like, very phase cell nuclei parallel to long diameter, coarse nuclear chromatin, cells may constitute a quasi-circular the gland cavity.
Clinical and pathological classification of esophageal adenocarcinoma (2) esophageal gland squamous cell carcinoma. This type of adenocarcinoma, gland spines previously known as squamous metaplasia of cancer or cancer has, in recent years, the concept gradually clear.
gland spine cancer. In more associated with adenocarcinoma of the small pieces of squamous cell carcinoma nests showed a malignant adenocarcinoma, showed less cytoplasm, larger nuclei, nuclear atypia obvious. In adenocarcinoma, a well-differentiated squamous epithelial cells, abundant cytoplasm, nuclear small, the same type, and even see the bridge or keratinized material between cells appears. The good squamous epithelium, showed a benign form.
gland squamous cell carcinoma. Originated in different parts of the adenocarcinoma and squamous cell carcinoma, a tumor in the body co-exist, the share of different parts, jagged, that the two were transitional state. Showed squamous and columnar epithelium was malignant, the two cells were atypia.
Clinical and pathological classification of esophageal adenocarcinoma (3) adenoid cystic carcinoma of the esophagus. This cancer is also called cylindrical tumor, adenoid basal cell carcinoma, cribriform cell carcinoma. This cancer is common in salivary gland, occurred in the esophagus are small. Cancer was in pieces, arranged in varying sizes arranged in cancer tissue cysts, cyst cell flat, capsule with mucus within Yin. Basaloid squamous cell carcinoma should be differentiated.
Clinical and pathological classification of esophageal adenocarcinoma (4), mucoepidermoid carcinoma of the esophagus. Originated in the esophageal mucous gland, the cancer is less common, the higher the degree of malignancy, often has extensive infiltration and metastasis. Cancer from the gland ducts or acini, composed of two different types of cells formed: one for the epidermal cells, cancer cells were polygonal, epithelioid cytoplasm or was squamous, or basal cell sample was small, more consistent cell size and shape, deeply stained nuclei, mitotic little; the other is the high differentiation of columnar epithelial cells, abundant clear cytoplasm, larger cells, the nucleus round, smaller, more consistent size and shape, nuclear at the base of the high columnar cells, cancer tissue with large and small, irregular luminal-like shape. The existence of these two cells were mixed, while the epidermal cells normally found in the basal columnar cells.

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